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Toplam kayıt 10, listelenen: 1-10
The evaluation of the therapeutic effect of memantine in sepsis induced critical illness polyneuropathy
(İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi Psikiyatri Kliniği, 2015)
Objectives: The purpose of our study is to investigate the effects of the different dosage of memantine for the treatment of Critical Illness Polyneuropathy (CIP) in rats that have surgically induced sepsis, by using ...
Levetiracetam attenuates rotenone-induced toxicity: A rat model of Parkinson's disease.
(Elsevier, 2016)
Levetiracetam (LEV), a second-generation anti-epileptic drug, is used for treatment of both focal and generalized epilepsy. Growing body of evidence suggests that LEV may have neuroprotective effects. The present study was ...
Nephro-protective effect of granulocyte colony-stimulating factor in streptozotocin induced diabetic rats
(Informahealthcare, 2014)
Diabetic nephropathy is one of the most serious complications of diabetes and the major cause of end-stage renal failure. Consequences of diabetic nephropathy include increased kidney size and glomerular volume, thickening ...
Montelukast inhibits pentylenetetrazol-induced seizures in rats.
(Medical Science International, 2015)
Background: Montelukast is an antiinflammatory drug with an antioxidant property. In this study, we aimed to reveal whether montelukast has a preventive effect against seizures and post-seizure oxidative stress in ...
Antipsychotic-like effect of agomelatine in a rodent model
(Yerküre Tanıtım ve Yayıncılık Hizmetleri, 2015)
Objective: Agomelatine is a naphthalene bioisostere of melatonin. Melatonin is involved in several neurophysiological systems; nevertheless, data about the relationship between melatonin and psychosis such as schizophrenia ...
Protective effect of edaravone against manganese-induced toxicity in cultured rat astrocytes.
(Elsevier, 2015)
Manganese (Mn), a trace metal, is essential for maintaining the normal regulation of many biochemical and cellular processes. However, accumulation of Mn due to excessive environmental exposure leads to neurological ...
Anti-Inflammatory and Anti-Fibrotic Effects of Ursodeoxycholic Acid in Streptozocin-Induced Diabetic Rats
(2020)
INTRODUCTION: Diabetic cardiomyopathy is a consequenceof free fatty acid oxidation, dysfunction in mitochondria,oxidative stress and diffuse myocardial fibrosis. We aimed toinvestigate the anti-inflammatory and anti-fibrotic ...
Pentilentetrazol ile Sıçanlarda Oluşturulan Deneysel Epilepsi Modelinde Oksolamin Sitratın Antikonvulsan Etkisi
(2020)
Amaç: Dünya çapında milyonlarca kişi epilepsi hastasıolarak sorun yaşamaktadır ve hastaların %25'inde şu andamevcut bulunan antiepileptik ilaçlara karşı dirençli nöbetlergözlenmektedir. Bu nedenlerle, halen etkili ve tolere ...
Effect of celecoxib on intra-abdominal sepsis-induced lung injury in rats
(2023)
Objectives: This experimental study investigated the preventive effects of Celecoxib, a selective COX-2 inhibitor, on lung injury induced by intra-abdominal sepsis in rats. The study assessed Celecoxib's potential to ...
Preventive Effect of Edaravone Against Ischemia-Reperfusion Injury in Rat Epigastric Island Flaps: An Experimental Study
(2023)
Objective Ischemia-reperfusion (I/R) injury is tissue damage occurring when blood returns to a tissue after an ischemic phase. Reperfusion initiates a cascade of acute inflammatory processes that end in cell death, tissue ...