dc.contributor.author | Akdal, Gulden | |
dc.contributor.author | Toydemir, Hulya Ertasoglu | |
dc.contributor.author | Saatci, Ali Osman | |
dc.contributor.author | Uygunoglu, Ugur | |
dc.contributor.author | Altunrende, Burcu | |
dc.contributor.author | Saip, Sabahattin | |
dc.contributor.author | Akman-Demir, Gulsen | |
dc.date.accessioned | 2019-08-13T12:10:23Z | |
dc.date.accessioned | 2019-08-13T15:55:41Z | |
dc.date.available | 2019-08-13T12:10:23Z | |
dc.date.available | 2019-08-13T15:55:41Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 2332-7812 | |
dc.identifier.uri | https://dx.doi.org/10.1212/NXI.0000000000000490 | |
dc.identifier.uri | http://hdl.handle.net/11446/2099 | |
dc.description | 13th Meeting of European-Neuro-Ophthalmological-Society (EUNOS) -- SEP 10-13, 2017 -- Budapest, HUNGARY | en_US |
dc.description | WOS: 000453672900017 | en_US |
dc.description | PubMed ID: 30175164 | en_US |
dc.description.abstract | Objective We present the clinical profile, features, and neuroimaging findings of 25 patients with Behcet disease (BD), and optic neuropathy (ON), which has been rarely reported in BD. Methods Data from 5 university hospitals were retrospectively reviewed, and patients with BD and ON were evaluated. There were 2 groups: (1) those already diagnosed with BD when ON developed (BD -> ON group) and (2) those diagnosed with BD during the evaluation of ON (ON -> BD group). Results There were 25 BD patients with ON (13 males). Among these, 13 had ON -> BD, and 12 had BD -> ON. Seventeen patients had unilateral ON, and 7 patients had recurrent ON. BD -> ON patients were older. Disc edema was seen more in ON -> BD than in BD -> ON patients (10 vs 3). Fourteen patients also had uveitis, 7 with BD -> ON and 7 with ON -> BD. There was other neurologic involvement in 8 patients; in the BD -> ON group, 4/4 had MS-like disease, in the ON -> BD group, 3 had typical parenchymal BD, and 1 had MS-like disease. Twenty of 21 patients received immunosuppressive medications, corticosteroids, or both. Prognosis was favorable in most: vision improved in 20 patients, more often in those receiving combined therapies. Conclusion BD may be diagnosed earlier if it is considered and investigated during the assessment of ON, particularly in high-risk regions. Prognosis of ON related to BD seems to be favorable. Immunosuppressants should be given along with corticosteroids. MS-like presentations should also be kept in mind in patients with BD and ON. | en_US |
dc.description.sponsorship | European Neuro Ophthalmol Soc, Expert Qual Congress Travel Agcy Ltd | en_US |
dc.language.iso | eng | en_US |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | en_US |
dc.identifier.doi | 10.1212/NXI.0000000000000490 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.title | Characteristics of optic neuropathy in Behcet disease | en_US |
dc.type | article | en_US |
dc.relation.journal | NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION | en_US |
dc.department | DBÜ | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.volume | 5 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.department-temp | [Akdal, Gulden] Dokuz Eylul Univ, Fac Med, Dept Neurol, Izmir, Turkey -- [Akdal, Gulden] Dokuz Eylul Univ, Inst Hlth Sci, Dept Neurosci, Izmir, Turkey -- [Toydemir, Hulya Ertasoglu] Bakirkoy Dr Sadi Konuk Training & Res Hosp, Dept Neurol, Istanbul, Turkey -- [Saatci, Ali Osman -- Yaman, Aylin -- Bajin, Meltem Soylev] Dokuz Eylul Univ, Fac Med, Dept Ophthalmol, Izmir, Turkey -- [Uygunoglu, Ugur -- Saip, Sabahattin -- Siva, Aksel] Istanbul Univ, Cerrahpasa Fac Med, Dept Neurol, Istanbul, Turkey -- [Altunrende, Burcu -- Akman-Demir, Gulsen] Bilim Univ, Dept Neurol, Fac Med, Istanbul, Turkey -- [Keskinoglu, Pembe] Dokuz Eylul Univ, Fac Med, Dept Biostat, Izmir, Turkey -- [Yilmaz, Suzan Guven] Ege Univ, Fac Med, Dept Ophthalmol, Izmir, Turkey -- [Celebisoy, Nese] Ege Univ, Fac Med, Dept Neurol, Izmir, Turkey | en_US |