dc.contributor.author | Kaba, Erkan | |
dc.contributor.author | Ozkan, Berker | |
dc.contributor.author | Erus, Suat | |
dc.contributor.author | Duman, Salih | |
dc.contributor.author | Cimenoglu, Berk | |
dc.contributor.author | Toker, Alper | |
dc.date.accessioned | 2019-08-13T12:10:23Z | |
dc.date.accessioned | 2019-08-13T15:56:05Z | |
dc.date.available | 2019-08-13T12:10:23Z | |
dc.date.available | 2019-08-13T15:56:05Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 1341-1098 | |
dc.identifier.issn | 2186-1005 | |
dc.identifier.uri | https://dx.doi.org/10.5761/atcs.oa.17-00108 | |
dc.identifier.uri | http://hdl.handle.net/11446/2214 | |
dc.description | WOS: 000427020500002 | en_US |
dc.description | PubMed ID: 29225302 | en_US |
dc.description.abstract | Purpose: To analyze the role of surgery in patients with Masaoka stage IVa thymoma treated with multimodality therapy. Methods: Of 191 patients undergoing surgery for thymoma in our department between January 2002 and December 2015, 39 (20.4%) had Masaoka stage IVa. Histopathological tumor type, myasthenic status of the Osserman-Genkins score, Masaoka stage at the first surgery, neoadjuvant treatment, number and type of surgeries, and survival rates were recorded. Results: Thymoma B2 was the most common histopathological tumor type (n = 16, 41%). Twenty-six (66.7%) patients underwent primary surgeries for Masaoka stage IVa thymoma, whereas nine (23.1%) underwent secondary surgeries and four (10.3%) underwent tertiary surgeries for pleural or pericardial recurrences. Median survival was 132 +/- 25 (82-181; 95% confidence interval [CI]) months. Overall 3-, 5-, and 10-year survival rates were 93%, 93%, and 56%, respectively. Conclusion: Surgical treatment should be considered as a completion modality to oncological therapy and has the potential to provide long-term survival of Masaoka stage IVa in patients with thymoma. The type of surgery should be determined based on the invasiveness of the lesion. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | MEDICAL TRIBUNE INC | en_US |
dc.identifier.doi | 10.5761/atcs.oa.17-00108 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | thymoma | en_US |
dc.subject | surgery | en_US |
dc.subject | Masaoka stage IVa | en_US |
dc.title | Role of Surgery in the Treatment of Masaoka Stage IVa Thymoma | en_US |
dc.type | article | en_US |
dc.relation.journal | ANNALS OF THORACIC AND CARDIOVASCULAR SURGERY | en_US |
dc.department | DBÜ | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.volume | 24 | en_US |
dc.identifier.startpage | 6 | en_US |
dc.identifier.endpage | 12 | en_US |
dc.contributor.authorID | 0000-0002-0793-8152 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.department-temp | [Kaba, Erkan] Istanbul Bilim Univ, Med Fac, Dept Thorac Surg, TR-34381 Istanbul, Turkey -- [Ozkan, Berker -- Erus, Suat -- Duman, Salih -- Cimenoglu, Berk -- Toker, Alper] Istanbul Univ, Istanbul Med Sch, Dept Thorac Surg, Istanbul, Turkey -- [Toker, Alper] Grp Florence Nightingale Hosp, Dept Thorac Surg, Istanbul, Turkey | en_US |