Yazar "İsbir, Turgay" için Tıp Fakültesi Makale Koleksiyonu listeleme
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Association between FAS and FASL genetic variants and risk of primary brain tumor
Dalan, Altay Burak; Timirci-Kahraman, Özlem; Turan, Saime; Kafadar, Ali Metin; Yaylım, İlhan; Ergen, Arzu; İsbir, Turgay (Informahealthcare, 2014)The purpose of this study was to investigate whether functional polymorphisms of apoptosis pathway genes FAS and FASL are associated with the development of primary brain tumors. The study constituted 83 patients with ... -
Cox-2 gene polymorphism and IL-6 levels in coronary artery disease
Ol, K.K.; Ağaçhan, Bedia; Görmüş, Uzay; Toptaş, Bahar; İsbir, Turgay (Funpec-Editora, 2011)Coronary artery disease is one of the leading causes of mortality and diabetes mellitus is one of its main risk factors due to microvascular and macrovascular complications, such as atherosclerosis. Atherosclerosis is now ... -
Expression levels of elastin and related genes in human varicose veins
Görmüş, Uzay; Timirci-Kahraman, Özlem; Ergen, Arzu; Kunt, A. T.; İsbir, Selim; Dalan, A. Burak; İsbir, Turgay (2014)Among the suspected reasons for varicose vein formation are changes in the quantity and content of the elastin protein; however, comprehensive investigations about elastin assembly in varicose vein formation are yet ... -
Fas-1377 A/G polymorphism in lung cancer
Görmüş, Uzay; Ergen, Arzu; Yaylım-Eraltan, İlhan; Yılmaz, Hülya; Turna, Akif; Bozkurt, Nilüfer; İsbir, Turgay (International Institute of Anticancer Research, 2007)Background: Reduced expression of Fas and/or increased expression of FasL is known to exist in some cancer types including lung cancer, so the Fas/FasL system may play a role in the course of cancer. Lack of cell surface ... -
Fas-1377A/G and fasL-844 T/C gene polymorphisms and epithelial ovarian cancer
Görmüş, Uzay; Ergen, Arzu; Yılmaz, Hülya; Dalan, Burak; Berkman, Sinan; İsbir, Turgay (International Institute of Anticancer Research, 2007)BACKGROUND: The Fas receptor is known to be widely expressed in various tissues and FasL is highly expressed on cells of the immune system and also on cells of immune-privileged areas such as the eyes and brain. Ovarian ... -
Leptin and leptin receptor polymorphisms are related to body mass index in a Turkish population
Görmüş, Uzay; Timirci-Kahraman, Özlem; Toptaş, Bahar; İsbir, Turgay; Çiftçi, Çavlan; Berkkan, Hasan Hakan; Karatay, Mutia Canan (TUBİTAK, 2014)Background/aim: Leptin is a hormone that is known to be related to weight gain and obesity. The soluble leptin receptor has been found in plasma as an important determinant of leptin sensitivity. In this study, our goal ...