Yazar "Erbaş, Oytun" için Tıp Fakültesi Makale Koleksiyonu listeleme
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Antipsychotic-like effect of agomelatine in a rodent model
Erbaş, Oytun; Eliküçük, Betül; Solmaz, Volkan; Akseki, Hüseyin Serdar; Semiz, Murat (Yerküre Tanıtım ve Yayıncılık Hizmetleri, 2015)Objective: Agomelatine is a naphthalene bioisostere of melatonin. Melatonin is involved in several neurophysiological systems; nevertheless, data about the relationship between melatonin and psychosis such as schizophrenia ... -
Beneficial effects of agomelatine in experimental model of sepsis-related acute kidney injury.
Başol, Nurşah; Erbaş, Oytun; Çavuşoğlu, Türker; Meral, Ayfer; Ateş, Utku (Ulusal Travma ve Acil Cerrahi Derneği, 2016)Background: Sepsis-related acute kidney injury (AKI) is a serious complication of sepsis. Problems persist regarding early diagnosis and treatment of AKI. The aim of the present study was to evaluate the efficacy of ... -
The evaluation of the therapeutic effect of memantine in sepsis induced critical illness polyneuropathy
Solmaz, Volkan; Piri Çınar, Bilge; Uyanıkgil, Yiğit; Çavuşoğlu, Türker; Peker, Gönül; Erbaş, Oytun (İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi Psikiyatri Kliniği, 2015)Objectives: The purpose of our study is to investigate the effects of the different dosage of memantine for the treatment of Critical Illness Polyneuropathy (CIP) in rats that have surgically induced sepsis, by using ... -
Levetiracetam attenuates rotenone-induced toxicity: A rat model of Parkinson's disease.
Erbaş, Oytun; Yılmaz, Mustafa; Taşkıran, Dilek (Elsevier, 2016)Levetiracetam (LEV), a second-generation anti-epileptic drug, is used for treatment of both focal and generalized epilepsy. Growing body of evidence suggests that LEV may have neuroprotective effects. The present study was ... -
Montelukast inhibits pentylenetetrazol-induced seizures in rats.
Çevik, Betül; Solmaz, Volkan; Aksoy, Dürdane; Erbaş, Oytun (Medical Science International, 2015)Background: Montelukast is an antiinflammatory drug with an antioxidant property. In this study, we aimed to reveal whether montelukast has a preventive effect against seizures and post-seizure oxidative stress in ... -
Nephro-protective effect of granulocyte colony-stimulating factor in streptozotocin induced diabetic rats
Erbaş, Oytun; Yapışlar, Hande; Oltulu, Fatih; Yavaşoğlu, Altuğ; Aktuğ, Hüseyin; Taşkıran, Dilek (Informahealthcare, 2014)Diabetic nephropathy is one of the most serious complications of diabetes and the major cause of end-stage renal failure. Consequences of diabetic nephropathy include increased kidney size and glomerular volume, thickening ... -
Protective effect of edaravone against manganese-induced toxicity in cultured rat astrocytes.
Evren, Vedat; Apaydın, Melda; Khalilnezhad, Asghar; Erbaş, Oytun; Taşkıran, Dilek (Elsevier, 2015)Manganese (Mn), a trace metal, is essential for maintaining the normal regulation of many biochemical and cellular processes. However, accumulation of Mn due to excessive environmental exposure leads to neurological ... -
Rebaudioside A inhibits pentylenetetrazol-induced convulsions in rats
Uyanıkgil, Yiğit; Çavuşoğlu, Türker; Balcıoğlu, Hüseyin A; Gürgül, Serkan; Solmaz, Volkan; Özlece, Hatice K; Erbaş, Oytun (Elsevier, 2016)The safety of patients with epilepsy consuming sweetening agents, which is becoming increasingly prevalent for various reasons, is a topic that should be emphasized as sensitively as it is for other diseases. Patients with ...