Yazar "Hançer, Veysel Sabri" için Tıp Fakültesi Makale Koleksiyonu listeleme
-
ADAMTS-13 gene expression in antiphospholipid syndrome
Hançer, Veysel Sabri; Diz-Küçükkaya, Reyhan; Topal-Sarıkaya, Ayşegül (Galenos Yayınevi, 2011)Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by recurrent thrombosis and fetal mortality. Thrombotic microangiopathy (TMA) is an important histological finding in catastrophicAPS (CAPS) and in ... -
Comparison of KRAS Mutation Tests in Colorectal Cancer Patients
Hançer, Veysel Sabri; Büyükdoğan, Murat; Türkmen, İlknur; Başsüllü, Nuray; Altuğ, Tuncay; Diz-Küçükkaya, Reyhan; Demir, Osman Gökhan (2011)The KRAS pathway and studies evaluating KRAS as a prognostic marker in colorectal cancer are discussed along with advances in KRAS gene mutation testing. Highly sensitive real-time polymerase chain reaction (PCR) methods ... -
Coronary artery ectasia is associated with the c.894G>T (Glu298Asp) polymorphism of the endothelial nitric oxide synthase gene.
Yalçın, Ahmet Arif; Aktürk, Ibrahim Faruk; Çelik, Ömer; Ertürk, Mehmet; Hançer, Veysel Sabri; Yalçın, Burce; Bıyık, Ismail (J-STAGE, Japan Science and Technology Information Aggregator, 2014)Coronary artery ectasia (CAE) is characterized by inappropriate dilation of the coronary vasculature. The underlying mechanisms of CAE formation are not yet entirely known. A polymorphism in the endothelial nitric oxide ... -
Cytotoxic T lymphocyte antigen-4 (CTLA-4) A49G polymorphism and autoimmune blood diseases
Aktürk, Faruk; Hançer, Veysel Sabri; Diz-Küçükkaya, Reyhan (Türk Hematoloji Deerneği, 2010)Objective: The cytotoxic T lymphocyte associated antigen-4 (CTLA-4) is expressed on T lymphocytes, and inhibits the T-cell responses. In animal models, it has been shown that complete CTLA-4 deficiency was lethal due to ... -
Eculizumab therapy in a child with hemolytic uremic syndrome and CFI mutation
Çaycı, F. Şemsa; Çakar, Nilgün; Hançer, Veysel Sabri; Uncu, Nermin; Acar, Banu; Gür, Gökçe (Springer Verlag, 2012)Background Hemolytic uremic syndrome (HUS) is the most common cause of acute renal failure in childhood. It usually occurs after a prodromal episode of diarrhea and it leads to significant morbidity and mortality during ... -
MPL W515L/K mutations in chronic myeloproliferative neoplasms
Akpınar, Timur Selçuk; Hançer, Veysel Sabri; Nalçacı, Meliha; Diz-Küçükkaya, Reyhan (Galenos Yayınevi, 2013)The MPL gene encodes the thrombopoietin receptor. Recently MPL mutations (MPL W515L or MPL W515K) were described in patients with essential thrombocythemia (ET) and primary (idiopathic) myelofibrosis (PMF). The prevalence ... -
Neurologic involvement in atypical hemolytic uremic syndrome and successful treatment with eculizumab
Gülleroğlu, Kaan; Fidan, Kibriya; Hançer, Veysel Sabri; Bayrakcı, Umut; Baskın, Esra; Söylemezoğlu, Oğuz (Springer Verlag, 2013)Background Atypical hemolytic uremic syndrome (aHUS) is associated with defective regulation of the complement pathway. Neurological involvement is the most common extrarenal complication and represents a major cause of ... -
Prophylactic eculizumab use in kidney transplantation: A review of the literature and report of a case with atypical hemolytic uremic syndrome.
Kasapoğlu, Umut; Ruhi, Çağlar; Tuğcu, Murat; Boynueğri, Başak; Titiz, İzzet; Hançer, Veysel Sabri; Apaydın, Süheyla (Springer Verlag, 2015)Background: Atypical hemolytic uremic syndrome (aHUS) is a very rare disease, which presents with microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. Progression to end-stage renal disease (ESRD) ... -
The relationship between P-Selectin polymorphisms and thrombosis in antiphospholipid syndrome: A pilot case-control study
Alpay, Nilüfer; Hançer, Veysel Sabri; Erer, Burak; İnanç, Murat; Diz-Küçükkaya, Reyhan (Galenos Yayınevi, 2014)Objective: The selectins are cell adhesion molecules that mediate the interactions among leukocytes, activated platelets, and endothelial cells. We aimed to investigate whether P-selectin polymorphisms are associated with ... -
Renal outcome with eculizumab in two diarrhea-associated hemolyticeuremic syndrome cases with severe neurologic involvement
Ekinci, Zelal; Bek, Kenan; Aytaç, Mehmet Baha; Karadenizli, Aynur; Hançer, Veysel Sabri (Elsevier, 2014)The kidney and brain are the two target organs in patients with Shiga toxin-producing Escherichia coli-associated hemolytic–uremic syndrome (STEC-HUS). Activation of the alternative complement pathway occurs in patients ...