Ara
Toplam kayıt 5, listelenen: 1-5
MPL W515L/K mutations in chronic myeloproliferative neoplasms
(Galenos Yayınevi, 2013)
The MPL gene encodes the thrombopoietin receptor. Recently MPL mutations (MPL W515L or MPL W515K) were described in patients with essential thrombocythemia (ET) and primary (idiopathic) myelofibrosis (PMF). The prevalence ...
Cytotoxic T lymphocyte antigen-4 (CTLA-4) A49G polymorphism and autoimmune blood diseases
(Türk Hematoloji Deerneği, 2010)
Objective: The cytotoxic T lymphocyte associated antigen-4 (CTLA-4) is expressed on T lymphocytes, and inhibits the T-cell responses. In animal models, it has been shown that complete CTLA-4 deficiency was lethal due to ...
ADAMTS-13 gene expression in antiphospholipid syndrome
(Galenos Yayınevi, 2011)
Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by recurrent thrombosis and fetal mortality. Thrombotic microangiopathy (TMA) is an important histological finding in catastrophicAPS (CAPS) and in ...
Comparison of KRAS Mutation Tests in Colorectal Cancer Patients
(2011)
The KRAS pathway and studies evaluating KRAS as a prognostic marker in colorectal cancer are discussed along with advances in KRAS gene mutation testing. Highly sensitive real-time polymerase chain reaction (PCR) methods ...
The relationship between P-Selectin polymorphisms and thrombosis in antiphospholipid syndrome: A pilot case-control study
(Galenos Yayınevi, 2014)
Objective: The selectins are cell adhesion molecules that mediate the interactions among leukocytes, activated platelets, and endothelial cells. We aimed to investigate whether P-selectin polymorphisms are associated with ...