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Is administration of trastuzumab an independent risk factor for developing osteonecrosis of the jaw among metastatic breast cancer patients under zoledronic acid treatment?
(Lippincott, Williams & Wilkins, 2015)
One of the most important adverse effects of zoledronic acid (ZA) is osteonecrosis of the jaw (ONJ). In previous literature, several risk factors have been identified in the development of ONJ. In this study, we aimed to ...
True local recurrences after breast conserving surgery have poor prognosis in patients with early breast cancer.
(Cureus Inc., 2016)
Background: This study was aimed at investigating clinical and histopathologic features of ipsilateral breast tumor recurrences (IBTR) and their effects on survival after breast conservation therapy.
Methods: 1,400 patients ...