dc.contributor.author | Celiksular, M. Cem | |
dc.contributor.author | Saracoglu, Ayten | |
dc.contributor.author | Yentur, Ercument | |
dc.date.accessioned | 2019-08-13T12:10:23Z | |
dc.date.accessioned | 2019-08-13T15:57:12Z | |
dc.date.available | 2019-08-13T12:10:23Z | |
dc.date.available | 2019-08-13T15:57:12Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 2149-0937 | |
dc.identifier.issn | 2149-276X | |
dc.identifier.uri | https://dx.doi.org/10.5152/TJAR.2016.65265 | |
dc.identifier.uri | http://hdl.handle.net/11446/2470 | |
dc.description | WOS: 000384014400002 | en_US |
dc.description | PubMed ID: 27366573 | en_US |
dc.description.abstract | Objective: The effects of oral carbohydrate solutions, ingested 2 h prior to operation, on stress response were studied in patients undergoing general or epidural anaesthesia. Methods: The study was performed on 80 ASA I-II adult patients undergoing elective total hip replacement, which were randomized to four groups (n=20). Group G patients undergoing general anaesthesia fasted for 8 h preoperatively; Group GN patients undergoing general anaesthesia drank oral carbohydrate solutions preoperatively; Group E patients undergoing epidural anaesthesia fasted for 8 h and Group EN patients undergoing epidural anaesthesia drank oral carbohydrate solutions preoperatively. Groups GN and EN drank 800 mL of 12.5% oral carbohydrate solution at 24: 00 preoperatively and 400 mL 2 h before the operation. Blood samples were taken for measurements of glucose, insulin, cortisol and IL-6 levels. Results: The effect of preoperative oral carbohydrate ingestion on blood glucose levels was not significant. Insulin levels 24 h prior to surgery were similar; however, insulin levels measured just before surgery were 2-3 times higher in groups GN and EN than in groups G and E. Insulin levels at the 24th postoperative hour in epidural groups were increased compared to those at basal levels, although general anaesthesia groups showed a decrease. From these measurements, only the change in Group EN was statistically significant (p< 0.05). Plasma cortisol levels at the 2nd peroperative hour were higher in epidural groups than in general anaesthesia groups. Both anaesthesia techniques did not have an effect on IL-6 levels. Conclusion: We concluded that epidural anaesthesia suppressed stress response, although preoperative oral carbohydrate nutrition did not reveal a significant effect on surgical stress response. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | AVES | en_US |
dc.identifier.doi | 10.5152/TJAR.2016.65265 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Stress response | en_US |
dc.subject | total hip replacement | en_US |
dc.subject | carbohydrate solution | en_US |
dc.subject | general anesthesia | en_US |
dc.subject | epidural anaesthesia | en_US |
dc.title | The Influence of Oral Carbohydrate Solution Intake on Stress Response before Total Hip Replacement Surgery during Epidural and General Anaesthesia | en_US |
dc.type | article | en_US |
dc.relation.journal | TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION | en_US |
dc.department | DBÜ | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.volume | 44 | en_US |
dc.identifier.startpage | 117 | en_US |
dc.identifier.endpage | 123 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.department-temp | [Celiksular, M. Cem -- Yentur, Ercument] Istanbul Univ, Dept Anaesthesiol & Reanimat, Cerrahpasa Med Sch, Istanbul, Turkey -- [Saracoglu, Ayten] Istanbul Bilim Univ, Dept Anaesthesiol Aad Reanimat, Sch Med, Istanbul, Turkey | en_US |