The long pentraxin-3 is a useful marker for diagnosis of ovarian torsion: An experimental rat model
dc.contributor.author | Akman, L. | |
dc.contributor.author | Erbas, O. | |
dc.contributor.author | Terek, M. C. | |
dc.contributor.author | Aktug, H. | |
dc.contributor.author | Taskiran, D. | |
dc.contributor.author | Askar, N. | |
dc.date.accessioned | 2019-08-13T12:10:23Z | |
dc.date.accessioned | 2019-08-13T15:57:20Z | |
dc.date.available | 2019-08-13T12:10:23Z | |
dc.date.available | 2019-08-13T15:57:20Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 0144-3615 | |
dc.identifier.issn | 1364-6893 | |
dc.identifier.uri | https://dx.doi.org/10.3109/01443615.2015.1086732 | |
dc.identifier.uri | http://hdl.handle.net/11446/2496 | |
dc.description | WOS: 000373739200033 | en_US |
dc.description | PubMed ID: 26470829 | en_US |
dc.description.abstract | Pentraxin-3 (PTX3) plays an important role in the primary inflammatory response. We aim to evaluate PTX3 as a diagnostic marker of ovarian torsion in an experimental rat model. In this study, 16 female Sprague Dawley albino mature rats were randomly allocated to Group 1 (control, sham operated) and Group 2 (experimental ovarian torsion model). A torsion model was set up using atraumatic vascular clips just above and below the right ovary for a 3-h ischaemia. Blood samples were collected before and three hours after ovarian torsion. Three hours after ovarian torsion, right ovary was surgically removed for histopathological examination in both groups. There was no significant difference in preoperative PTX3 level in both groups (1.05 +/- 0.20 ng/mL vs 1.09 +/- 0.28 ng/mL, p > 0.05). Three hours after the operation, mean plasma level of PTX3 was significantly higher in ovarian torsion group than the control group (2.13 +/- 0.49 ng/mL vs 1.07 +/- 0.22 ng/mL, p = 0.001). Also, the mean total histopathological score was significantly increased in the torsion group. PTX3 can be used in clinical practice as a useful marker for early diagnosis of ovarian torsion. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | TAYLOR & FRANCIS INC | en_US |
dc.identifier.doi | 10.3109/01443615.2015.1086732 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | diagnosis | en_US |
dc.subject | rat model | en_US |
dc.subject | ovarian torsion | en_US |
dc.subject | Pentraxin-3 | en_US |
dc.subject | biochemical marker | en_US |
dc.subject | PTX3 | en_US |
dc.title | The long pentraxin-3 is a useful marker for diagnosis of ovarian torsion: An experimental rat model | en_US |
dc.type | article | en_US |
dc.relation.journal | JOURNAL OF OBSTETRICS AND GYNAECOLOGY | en_US |
dc.department | DBÜ | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.volume | 36 | en_US |
dc.identifier.startpage | 399 | en_US |
dc.identifier.endpage | 402 | en_US |
dc.contributor.authorID | 0000-0002-4505-0939 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.department-temp | [Akman, L. -- Terek, M. C. -- Askar, N.] Ege Univ, Sch Med, Dept Obstet & Gynecol, TR-35100 Izmir, Turkey -- [Akman, L.] Ege Univ, Inst Hlth Sci, Dept Stem Cell, TR-35100 Izmir, Turkey -- [Erbas, O.] Bilim Univ, Sch Med, Dept Physiol, Istanbul, Turkey -- [Aktug, H.] Ege Univ, Sch Med, Dept Histol & Embryol, TR-35100 Izmir, Turkey -- [Taskiran, D.] Ege Univ, Sch Med, Dept Physiol, TR-35100 Izmir, Turkey | en_US |
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