dc.contributor.author | Guler, Necdet | |
dc.contributor.author | Unalp, Omer | |
dc.contributor.author | Guler, Ayse | |
dc.contributor.author | Yaprak, Onur | |
dc.contributor.author | Dayangac, Murat | |
dc.contributor.author | Sozbilen, Murat | |
dc.contributor.author | Tokat, Yaman | |
dc.date.accessioned | 2019-08-13T12:10:23Z | |
dc.date.accessioned | 2019-08-13T16:02:52Z | |
dc.date.available | 2019-08-13T12:10:23Z | |
dc.date.available | 2019-08-13T16:02:52Z | |
dc.date.issued | 2013 | |
dc.identifier.issn | 1499-3872 | |
dc.identifier.uri | https://dx.doi.org/10.1016/S1499-3872(13)60093-4 | |
dc.identifier.uri | http://hdl.handle.net/11446/2936 | |
dc.description | WOS: 000328005900004 | en_US |
dc.description | PubMed ID: 24322743 | en_US |
dc.description.abstract | BACKGROUND: The timing and selection of patients for liver transplantation in acute liver failure are great challenges. This study aimed to investigate the effect of Glasgow coma scale (GCS) and APACHE-II scores on liver transplantation outcomes in patients with acute liver failure. METHOD: A total of 25 patients with acute liver failure were retrospectively analyzed according to age, etiology, time to transplantation, coma scores, complications and mortality. RESULTS: Eighteen patients received transplants from live donors and 7 had cadaveric whole liver transplants. The mean duration of follow-up after liver transplantation was 39.86 +/- 40.23 months. Seven patients died within the perioperative period and the 1-, 3-, 5-year survival rates of the patients were 72%, 72% and 60%, respectively. The parameters evaluated for the perioperative deaths versus alive were as follows: the mean age of the patients was 33.71 vs 28 years, MELD score was 40 vs 32.66, GCS was 5.57 vs 10.16, APACHE-II score was 23 vs 18.11, serum sodium level was 138.57 vs 138.44 mmol/L, mean waiting time before the operation was 12 vs 5.16 days. Low GCS, high APACHE-II score and longer waiting time before the operation (P<0.01) were found as statistically significant factors for perioperative mortality. CONCLUSION: Lower GCS and higher APACHE-II scores are related to poor outcomes in patients with acute liver failure after liver transplantation. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | ZHEJIANG UNIV SCH MEDICINE | en_US |
dc.identifier.doi | 10.1016/S1499-3872(13)60093-4 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | liver transplantation | en_US |
dc.subject | acute liver failure | en_US |
dc.subject | APACHE-II | en_US |
dc.subject | waiting time | en_US |
dc.subject | Glasgow coma scale | en_US |
dc.title | Glasgow coma scale and APACHE-II scores affect the liver transplantation outcomes in patients with acute liver failure | en_US |
dc.type | article | en_US |
dc.relation.journal | HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL | en_US |
dc.department | DBÜ | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.volume | 12 | en_US |
dc.identifier.startpage | 589 | en_US |
dc.identifier.endpage | 593 | en_US |
dc.contributor.authorID | 0000-0002-1240-7233 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.department-temp | [Guler, Necdet -- Yaprak, Onur -- Dayangac, Murat -- Akyildiz, Murat -- Tokat, Yaman] Sisli Florence Nightingale Hosp, Organ Transplantat Ctr, Istanbul, Turkey -- [Unalp, Omer -- Sozbilen, Murat] Ege Univ, Sch Med, Dept Gen Surg, Izmir, Turkey -- [Guler, Necdet] Ege Univ, Sch Med, Dept Neurol, Izmir, Turkey -- [Akyildiz, Murat] Istanbul Bilim Univ, Dept Gastroenterol, Sch Med, Istanbul, Turkey | en_US |