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dc.contributor.authorTayyareci, Yelda
dc.contributor.authorYildirimturk, Ozlem
dc.contributor.authorAytekin, Vedat
dc.contributor.authorDemiroglu, I. C. Cemsid
dc.contributor.authorAytekin, Saide
dc.date.accessioned2019-08-13T12:10:23Z
dc.date.accessioned2019-08-13T16:04:42Z
dc.date.available2019-08-13T12:10:23Z
dc.date.available2019-08-13T16:04:42Z
dc.date.issued2010
dc.identifier.issn0742-2822
dc.identifier.issn1540-8175
dc.identifier.urihttps://dx.doi.org/10.1111/j.1540-8175.2009.01053.x
dc.identifier.urihttp://hdl.handle.net/11446/3355
dc.descriptionWOS: 000275757300008en_US
dc.descriptionPubMed ID: 20486957en_US
dc.description.abstractObjectives: Our aim was to evaluate subclinical left ventricular (LV) dysfunction, by two novel echocardiographic techniques, velocity vector imaging (VVI)-derived strain imaging and tissue Doppler imaging (TDI), in patients with asymptomatic, severe aortic regurgitation (AR). Methods: Forty patients with severe AR with normal ejection fraction and 30 controls were included to the study. All patients underwent a standard echocardiography extended with TDI and VVI analyses. To evaluate the LV longitudinal and circumferential deformation, segmental systolic peak strain and strain rate (SRs) data were acquired from parasternal short axis, apical four-chamber, two-chamber, and long axis views, and additionally LV myocardial velocities, isovolumic myocardial acceleration (IVA), peak systolic velocity (Sa) and peak myocardial velocity during isovolumic contraction (IVV) assessed by TDI. Results: IVA was the only TDI-derived parameter which was significantly impaired in AR patients (P = 0.0001). Both longitudinal and circumferential strain and SRs of the LV were significantly decreased in patients with severe AR (P = 0.0001). Longitudinal and circumferential strain/SRs and TDI-derived LV IVA were inversely correlated with LV end-diastolic diameter (P = 0.0001) and end-systolic diameter (P = 0.0001). TDI-derived IVA was also very well correlated with longitudinal deformation parameters (P = 0.0001). Conclusions: VVI- derived strain imaging and TDI-derived IVA may be used as adjunctive, reliable, noninvasive parameters for evaluating subclinical ventricular dysfunction in patients with chronic, severe AR. This may help to identify patients for closer follow-up and to determine the need for surgery before developing irreversible, severe heart failure. (Echocardiography 2010;27:260-268).en_US
dc.language.isoengen_US
dc.publisherWILEYen_US
dc.identifier.doi10.1111/j.1540-8175.2009.01053.xen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectaortic regurgitationen_US
dc.subjectechocardiographyen_US
dc.subjectleft ventricular functionen_US
dc.subjectstrain-strain rateen_US
dc.subjecttissue Doppler imagingen_US
dc.titleSubclinical Left Ventricular Dysfunction in Asymptomatic Severe Aortic Regurgitation Patients with Normal Ejection Fraction: A Combined Tissue Doppler and Velocity Vector Imaging Studyen_US
dc.typearticleen_US
dc.relation.journalECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUESen_US
dc.departmentDBÜen_US
dc.identifier.issue3en_US
dc.identifier.volume27en_US
dc.identifier.startpage260en_US
dc.identifier.endpage268en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.department-temp[Aytekin, Saide] Florence Nightingale Hosp, Dept Cardiol, Div Cardiol, TR-34381 Istanbul, Turkey -- [Aytekin, Vedat -- Aytekin, Saide] TC Istanbul Bilim Univ, Dept Cardiol, Istanbul, Turkeyen_US


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