Advanced Search

Show simple item record

dc.contributor.authorTuzun, Erdem
dc.contributor.authorPolat, Aslihan
dc.contributor.authorAkman-Demir, Gulsen
dc.contributor.authorKurtuncu, Murat
dc.contributor.authorMutlu, Melike
dc.contributor.authorAksay, Bahar
dc.contributor.authorEraksoy, Mefkure
dc.date.accessioned2019-08-13T12:10:23Z
dc.date.accessioned2019-08-13T16:04:46Z
dc.date.available2019-08-13T12:10:23Z
dc.date.available2019-08-13T16:04:46Z
dc.date.issued2010
dc.identifier.issn1300-0667
dc.identifier.urihttps://dx.doi.org/10.4274/npa.y5628
dc.identifier.urihttp://hdl.handle.net/11446/3367
dc.descriptionWOS: 000285883500011en_US
dc.description.abstractObjective: The association between stressful life events and subsequent multiple sclerosis (MS) attacks has been frequently reported with conflicting results. In this study, we investigated the impact of a common stressor on MS attacks. Methods: We prospectively evaluated the attack and disability status of 48 consecutive relapsing remitting (RRMS) or secondary progressive MS (SPMS) patients (Group 1) exposed to 1999 Izmit earthquake in comparison to 34 consecutive MS patients (Group 2) with similar demographic and clinical features and living outside the earthquake zone. Results: An increased proportion of patients had relapses in Group 1 within the 3month period after earthquake with no difference in EDSS in a 1year followup period. Furthermore, Group 1 patients with attacks exhibited significantly increased numbers of relapses in a 1year followup period compared to Group 1 patients without attacks and Group 2 patients with or without attacks. Alternatively, the average annual attack rates in Group 1 patients without attacks were significantly reduced. Logistic regression analysis revealed the exposure to earthquake as a predictor of MS attacks. There was no statistically significant association between MS attacks and occurrence of posttraumatic stress disorder. Conclusion: Our results suggest that stress has opposing effects on MS attacks in different patients.(Archives of Neuropsychiatry 2010; 47: 324-7)en_US
dc.language.isoengen_US
dc.publisherGALENOS YAYINCILIKen_US
dc.relation.isversionof10.4274/npa.y5628en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMultiple sclerosisen_US
dc.subjectearthquakeen_US
dc.subjectattacken_US
dc.subjectstressen_US
dc.titleImpact of Earthquake on Multiple Sclerosis Attacksen_US
dc.typearticleen_US
dc.relation.journalNOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRYen_US
dc.contributor.departmentDBÜen_US
dc.identifier.issue4en_US
dc.identifier.volume47en_US
dc.identifier.startpage324en_US
dc.identifier.endpage327en_US
dc.contributor.authorID0000-0001-6032-0856en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record