dc.contributor.author | Catakoglu, Alp Burak | |
dc.contributor.author | Aytekin, Vedat | |
dc.contributor.author | Demiroglu, Cemsid | |
dc.contributor.author | Aytekin, Saide | |
dc.date.accessioned | 2019-08-13T12:10:23Z | |
dc.date.accessioned | 2019-08-13T16:05:07Z | |
dc.date.available | 2019-08-13T12:10:23Z | |
dc.date.available | 2019-08-13T16:05:07Z | |
dc.date.issued | 2009 | |
dc.identifier.issn | 1734-1922 | |
dc.identifier.uri | http://hdl.handle.net/11446/3432 | |
dc.description | WOS: 000267405600008 | en_US |
dc.description.abstract | Introduction: Previous studies have demonstrated unfavourable outcomes in coronary artery disease and percutaneous coronary intervention (PCI) patients with high endothelin-1 (ET-1) or high sensitivity C-reactive protein (hs-CRP) levels. The aim of our study was to investigate the impact of pre-procedural ET-1 and hs-CRP levels on major adverse coronary events (MACE) after PCI and to analyse a possible correlation between ET-1 and hs-CRP in this study population. Material and methods: Eighty consecutive PCI patients with a single de novo, non-occlusive coronary lesion were included. Blood samples were obtained immediately before the procedure. The study endpoint was the occurrence of MACE, which was defined as death (all causes), non-fatal myocardial infarction or repeat coronary revascularization (PCI or surgery). Results: At the end of the 24 months' follow-up, 28 patients (35%) reached an end-point. We could not observe any correlation between ET-1 and hs-CRP in the overall patient group (r = 0.141, p = 0.213). Neither ET-1 nor hs-CRP levels were found to be predictive for MACE after PCI in multivariate analyses (p = 0.605 and 0.757 respectively). Conclusions: We could not demonstrate a relationship between pre-procedural ET-1 or hs-CRP levels and MACE at 24 months after successful PCI with single stent implantation to single de novo lesions. This study also could not show any correlation between ET-1 and hs-CRP levels in PCI patients. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | TERMEDIA PUBLISHING HOUSE LTD | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | endothelin-1 | en_US |
dc.subject | C-reactive protein | en_US |
dc.subject | percutaneous coronary intervention | en_US |
dc.subject | MACE | en_US |
dc.title | The interaction between endothelin-1 and C-reactive protein and their impact on long-term prognosis after percutaneous coronary interventions | en_US |
dc.type | article | en_US |
dc.relation.journal | ARCHIVES OF MEDICAL SCIENCE | en_US |
dc.department | DBÜ | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.volume | 5 | en_US |
dc.identifier.startpage | 38 | en_US |
dc.identifier.endpage | 44 | en_US |
dc.contributor.authorID | 0000-0002-1095-3513 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.department-temp | [Catakoglu, Alp Burak -- Aytekin, Vedat -- Demiroglu, Cemsid -- Aytekin, Saide] Istanbul Bilim Univ, Dept Cardiol, Florence Nightingale Hosp, Istanbul, Turkey | en_US |