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Toplam kayıt 45, listelenen: 31-40
Biallelic mutations in the 3 ' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing
(NATURE PUBLISHING GROUP, 2017)
Deadenylases are best known for degrading the poly(A) tail during mRNA decay. The deadenylase family has expanded throughout evolution and, in mammals, consists of 12 Mg2+-dependent 3'-end RNases with substrate specificity ...
Serum Toll-Like Receptor-2, Toll-Like Receptor-4 Levels in Patients with HBeAg-Negative Chronic Viral Hepatitis B
(MARY ANN LIEBERT, INC, 2017)
Toll-like receptors (TLRs) may play an important role in hepatitis-B pathogenesis. However, serum TLR-2 and TLR-4 levels and their association with serum liver enzymes, hepatitis B virus (HBV) DNA, quantitative HBsAg levels, ...
Short-term effects of intravitreal ranibizumab and bevacizumab administration on 24-h ambulatory blood pressure monitoring recordings in normotensive patients with age-related macular degeneration
(NATURE PUBLISHING GROUP, 2017)
Purpose To evaluate effects of intravitreal ranibizumab and bevacizumab administration on ambulatory blood pressure monitoring (ABPM) recordings in normotensive patients with age-related macular degeneration (AMD). Patients ...
Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function
(AMER SOC HEMATOLOGY, 2017)
Coagulation proteases have increasingly recognized functions beyond hemostasis and thrombosis. Disruption of activated protein C (aPC) or insulin signaling impair function of podocytes and ultimately cause dysfunction of ...
Treatment of ineffective endocardial defibrillation with subcutaneous array: a case report
(TURKISH SOC CARDIOLOGY, 2017)
Defibrillation threshold (DFT) testing is an important part of ICD implantation. After placement of the ICD generator, a DFT test is performed to evaluate the integrity of the ICD system and to confirm a successful ...
Neuroprotective effects of erythropoietin on Alzheimer's dementia model in rats
(WROCLAW MEDICAL UNIV, 2017)
Background. Although Alzheimer's disease (AD) is the most common age-related neurodegenerative disease and characterized by memory impairment, only symptomatic treatments are available. Objectives. Because recombinant human ...
Limbal Stem Cell Deficiency and Treatment with Stem Cell Transplantation
(TURKISH OPHTHALMOLOGICAL SOC, 2017)
The cornea is the outermost tissue of the eye and it must be transparent for the maintenance of good visual function. The superficial epithelium of the cornea, which is renewed continuously by corneal stem cells, plays a ...
MID-LONG TERM RESULTS OF MANIPULATION AND ARTHROSCOPIC RELEASE IN FROZEN SHOULDER
(ATHA COMUNICACAO & EDITORA, 2017)
Objective: Surgical treatment options should be discussed in cases of frozen shoulder, which is usually treated in a conservative manner. In this study, we evaluated the efficacy of manipulation and arthroscopic release ...
Topography and Higher Order Corneal Aberrations of the Fellow Eye in Unilateral Keratoconus
(TURKISH OPHTHALMOLOGICAL SOC, 2017)
Objectives: Comparison of topography and corneal higher order aberrations (HOA) data of fellow normal eyes of unilateral keratoconus patients with keratoconus eyes and control group. Materials and Methods: The records of ...
Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly
(NATURE PUBLISHING GROUP, 2017)
Recessive mutations in WD repeat domain 62 (WDR62) cause microcephaly and a wide spectrum of severe brain malformations. Disruption of the mouse ortholog results in microcephaly underlain by reduced proliferation of ...