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Toplam kayıt 15, listelenen: 1-10
Levetiracetam attenuates rotenone-induced toxicity: A rat model of Parkinson's disease.
(Elsevier, 2016)
Levetiracetam (LEV), a second-generation anti-epileptic drug, is used for treatment of both focal and generalized epilepsy. Growing body of evidence suggests that LEV may have neuroprotective effects. The present study was ...
Oxidative stress and cannabinoid receptor expression in type-2 diabetic rat pancreas following treatment with Δ9-THC
(Wiley Pub., 2014)
The objectives of study were (a) to determine alteration of feeding, glucose level and oxidative stress and (b) to investigate expression and localization of cannabinoid receptors in type-2 diabetic rat pancreas treated ...
Early life status epilepticus and stress have distinct and sex-specific effects on learning, subsequent seizure outcomes, including anticonvulsant response to phenobarbital.
(Wiley Pub., 2015)
Aims: Neonatal status epilepticus (SE) is often associated with adverse cognitive and epilepsy outcomes. We investigate the effects of three episodes of kainic acid-induced SE (3KA-SE) and maternal separation in immature ...
Distribution of pon L/M55 and Q/R192 genotypes in Turkish Patients with angiographically-defined coronary artery disease: Effects on serum lipids
(Türkiye Klinikleri, 2013)
Objective: Paraoxonase 1 (PON1) was suggested to lower the risk of coronary artery
disease (CAD) by preventing high-density lipoprotein-cholesterol (HDL-C) and low-density lipoprotein-cholesterol (LDL-C) oxidation during ...
Bronchoscopic treatment in the management of benign tracheal stenosis: Choices for simple and complex tracheal stenosis
(Elsevier, 2016)
Background:Bronchoscopic treatment is 1 of the treatment choices for both palliative and definitive treatment of benign tracheal stenosis. There is no consensus on the management of these patients, however, especially ...
Simvastatin induces apoptosis in human breast cancer cells: p53 and estrogen receptor independent pathway requiring signalling through JNK
(Elsevier, 2007)
The effect of simvastatin, a widely used statin for the treatment of hypercholesterolemia, was investigated in the estrogen receptor (ER)-positive MCF-7, and the ER-negative MDA-MB 231 human breast cancer cell lines. ...
The view of religious officials on organ donation and transplantation in the Zeytinburnu District of Istanbul.
(Springer Verlag, 2015)
One of the obstacles to organ donation and transplantation in Turkey is that of religious beliefs and, at this point, religious officials constitute a key aspect of this problem. Positive or negative viewpoints held by ...
Regulation of oxidative stress and somatostatin, cholecystokinin, apelin gene expressions by ghrelin in stomach of newborn diabetic rats
(Elsevier, 2013)
The aim of the study was to determine whether ghrelin treatment has a protective effect on gene expression and biochemical changes in the stomach of newborn streptozotocin (STZ) induced diabetic rats. In this study, four ...
Adjuvant chemoradiotherapy after D2 resection in gastric cancer: a single-center observational study.
(Springer Verlag, 2015)
Purpose: Previous studies demonstrated survival benefits in association with the addition of chemoradiotherapy after surgery in gastric cancer. This study aimed to examine the efficacy in terms of loco-regional control and ...
Antioxidant effect of carnosine treatment on renal oxidative stress in streptozotocin-induced diabetic rats.
(Taylor and Francis Online, 2014)
Nitric oxide (NO) plays a significant role in the development of diabetic nephropathy. We investigated the effects of an antioxidant, carnosine, on streptozotocin (STZ)-induced renal injury in diabetic rats. We used four ...