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Toplam kayıt 7, listelenen: 1-7
Highly selective SGLT2 inhibitor dapagliflozin reduces seizure activity in pentylenetetrazol-induced murine model of epilepsy
(BIOMED CENTRAL LTD, 2018)
Background: Worldwide, over 10 million individuals suffer from drug-resistant epilepsy. New therapeutic strategies are needed to address this debilitating disease. Inhibition of sodium-glucose linked transporters (SGLTs), ...
The evaluation of the therapeutic effect of memantine in sepsis induced critical illness polyneuropathy
(İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi Psikiyatri Kliniği, 2015)
Objectives: The purpose of our study is to investigate the effects of the different dosage of memantine for the treatment of Critical Illness Polyneuropathy (CIP) in rats that have surgically induced sepsis, by using ...
Montelukast inhibits pentylenetetrazol-induced seizures in rats.
(Medical Science International, 2015)
Background: Montelukast is an antiinflammatory drug with an antioxidant property. In this study, we aimed to reveal whether montelukast has a preventive effect against seizures and post-seizure oxidative stress in ...
Antipsychotic-like effect of agomelatine in a rodent model
(Yerküre Tanıtım ve Yayıncılık Hizmetleri, 2015)
Objective: Agomelatine is a naphthalene bioisostere of melatonin. Melatonin is involved in several neurophysiological systems; nevertheless, data about the relationship between melatonin and psychosis such as schizophrenia ...
Rebaudioside A inhibits pentylenetetrazol-induced convulsions in rats
(ELSEVIER TAIWAN, 2016)
The safety of patients with epilepsy consuming sweetening agents, which is becoming increasingly prevalent for various reasons, is a topic that should be emphasized as sensitively as it is for other diseases. Patients with ...
Accumulation of alpha-Synuclein in Cerebellar Purkinje Cells of Diabetic Rats and Its Potential Relationship with Inflammation and Oxidative Stress Markers
(HINDAWI PUBLISHING CORP, 2017)
Objective. The present study was conducted to evaluate the relationship between plasma oxidative stress markers such as malondialdehyde (MDA) and glutathione (GSH), inflammatory marker pentraxin-3 (PTX3), and cerebellar ...
Neuroprotective effects of erythropoietin on Alzheimer's dementia model in rats
(WROCLAW MEDICAL UNIV, 2017)
Background. Although Alzheimer's disease (AD) is the most common age-related neurodegenerative disease and characterized by memory impairment, only symptomatic treatments are available. Objectives. Because recombinant human ...