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Toplam kayıt 9, listelenen: 1-9
Regular exercise alleviates renovascular hypertension-induced cardiac/endothelial dysfunction and oxidative injury in rats
(Polish Physiological Society, 2016)
The importance of physical activity in the management of renovascular diseases is well-known, but lacks evidence of underlying mechanisms. The purpose of the study was to elucidate the protective/therapeutic effects of ...
Protective effect of quercetin against oxidative stress-induced toxicity associated with doxorubicin and cyclophosphamide in rat kidney and liver tissue
(Iranian Society of Nephrology, 2017)
Introduction. Doxorubicin and cyclophosphamide are widely used anticancer drugs with substantial toxicity in noncancerous tissue resulting from oxidative damage. Quercetin is a potent antioxidant compound. We hypothesized ...
The efficacy of Aesculus hippocastanum seeds on diabetic nephropathy in a streptozotocin-induced diabetic rat model
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2016)
Cytokines, such as transforming growth factor (TGF)-beta 1, and increased oxidative stress are considered to be responsible for the development of diabetic nephropathy. We hypothesized that Aesculus hippocastanum (AH) seeds ...
The effects of antioxidant combination on indomethacin-induced gastric mucosal injury in rats
(NLM (Medline), 2019)
The aim of this study is an investigation the protective effects of vitamin C (Vit C), vitamin E (Vit E), ?-carotene, sodium selenate combination in indomethacin-induced gastric mucosal damage in rats. Rats were divided ...
CB-1R and GLP-1R gene expressions and oxidative stress in the liver of diabetic rats treated with sitagliptin
(POLISH ACAD SCIENCES INST PHARMACOLOGY, 2017)
Background: Type 2 diabetes is a major health problem affecting millions of people.Controlled eating and regular physical activity are important for the management of type 2 diabetes. Dipeptidyl peptidase-4 enzyme (DPP-4) ...
Neuroprotective effects of chronic administration of levetiracetam in a rat model of diabetic neuropathy
(ELSEVIER IRELAND LTD, 2016)
Objective: Diabetic neuropathy (DNP) is a frequent and serious complication of diabetes mellitus (DM) that leads to progressive and length-dependent loss of peripheral nerve axons. The purpose of the present study is to ...
Oxytocin provides protection against diabetic polyneuropathy in rats
(TAYLOR & FRANCIS LTD, 2017)
Purpose: The aim of the present study is to investigate the protective effects of oxytocin (OT) on diabetic neuropathy (DNP) in rats. Materials and methods: Eighteen rats were used to induce diabetes using single dose ...
An Investigation into the Protective Effects of Various Doses of Boric Acid on Liver, Kidney, and Brain Tissue Damage Caused by High Levels of Acute Alcohol Consumption
(Springernature, 2023)
Acute high-dose alcohol consumption can lead to oxidative stress, which can cause harm to organs. In this study we aim to determine whether administering boric acid (BA) can protect certain organs (liver, kidney, and brain) ...
Immunosuppressant Tacrolimus Treatment Delays Acute Seizure Occurrence, Reduces Elevated Oxidative Stress, and Reverses PGF2? Burst in the Brain of PTZ-Treated Rats
(Springer/Plenum Publishers, 2023)
It is still an urgent need to find alternative and effective therapies to combat epileptic seizures. Tacrolimus as a potent immunosuppressant and calcineurin inhibitor is emerging as promising drug to suppress seizures. ...