Ara
Toplam kayıt 11, listelenen: 1-10
Oktreotidin, sepsis modelinde sıçanların akciğerleri üzerindeki kısa dönem koruyucu etkisi
(NLM (Medline), 2022)
BACKGROUND: Acute respiratory distress syndrome is a devastating complication of severe sepsis. Preclinical models suggest that direct lung injury begins with attack to the lung epithelium, but indirect lung injury results ...
Antifibrotic preventive effect of polyethylene glycol (PEG) 3350 in methotrexate-induced hepatoxicity model
(Acta Cirurgica Brasileira, 2022)
Purpose: Liver damage caused by drugs and other chemicals accounts for about 5% of all cases. Methotrexate (MTX), a folic acid analogue, is a first-line synthetic antimetabolite agent routinely used in the treatment of ...
Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model
(Acta Cirurgica Brasileira, 2022)
Purpose: To investigate the effect of givinostat treatment in acetic acid-induced ulcerative colitis model in rats. Methods: Thirty male Wistar albino rats were used. Rats were randomly divided into three equal groups, and ...
Therapeutic effect of finasteride through its antiandrogenic and antioxidant role in a propionic acid-induced autism model: Demonstrated by behavioral tests, histological findings and MR spectroscopy
(Elsevier Ireland Ltd, 2022)
Background: Autism is a clinically defined neurodevelopmental disorder with unknown origin characterized by significant social, communication and behavioral challenges. Although it can be a lifelong condition, treatments ...
Vitamins C and E protect from sepsis-induced lung damage in rat and CT correlation
(Comenius University in Bratislava, 2022)
BACKGROUND: Sepsis is one of the leading causes of death in intensive care units worldwide. Vitamins C and E are natural antioxidants and anti-infl ammatory agents. Suppressing the infl ammation is an important treatment ...
Short-term protective effect of octreotide on the lungs of rats with experimentally induced sepsis
(Turkish Association of Trauma and Emergency Surgery, 2022)
BACKGROUND: Acute respiratory distress syndrome is a devastating complication of severe sepsis. Preclinical models suggest that direct lung injury begins with attack to the lung epithelium, but indirect lung injury results ...
Effect of chronic alcohol consumption on myocardial apoptosis in the rat model of isoproterenol-induced myocardial injury and investigation on the cardioprotective role of calpain inhibitor 1
(Taylor and Francis Ltd., 2022)
We investigated the presence of myocardial apoptosis on isoproterenol (ISO)-induced myocardial injury (MI) after long-term high dose alcohol consumption and examined the antiapoptotic role of calpain inhibitor 1. Male ...
The Efficacy of Hydrodilatation for the Prevention of Vasospasm following Microsurgical Anastomosis
(Thieme Medical Publishers, Inc., 2022)
Background âVasospasm is a major problem following microsurgical reconstruction which can result in the partial or complete loss of the flap tissue. The aim of this study was to investigate the efficiency of hydrodilatation ...
Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats
(Taylor and Francis Ltd., 2022)
Aim: Although the most common age-related neurodegenerative disease defined by memory loss is Alzheimer's disease (AD), only symptomatic therapies are present. A complex pathway for the AD pathogenesis that includes an ...
The therapeutic effect of ALT-711 on erectile function in rats treated with high-level AGEs (advanced glycation end products) containing diet
(Springer Nature, 2022)
To investigate, if advanced glycation end products (AGEs) are involved in erectile dysfunction (ED) and also ALT-711, a cross-link breaker of AGEs, has the therapeutic potential against the development of ED in rats treated ...