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Now showing items 1431-1440 of 1459
COSMC expression as a predictor of remission in IgA nephropathy
(Springer Science and Business Media B.V., 2023)
Purpose: The impact of core 1,3-galactosyltransferase-specific molecular chaperon (COSMC) gene expression and methylation profile on clinical progression of IgA nephropathy (IgAN) is unclear. The aim of this study was to ...
Ductal prostate cancer: Clinical features and outcomes from a multicenter retrospective analysis and overview of the current literature
(Lippincott Williams & Wilkins, 2022)
Objective The aim of the study is to evaluate clinical features and outcomes after different therapeutic strategies for ductal prostate adenocarcinoma (DPC), a rare but aggressive subtype of invasive prostate cancer (PCa) ...
Higher rates of cefiderocol resistance among NDM producing Klebsiella bloodstream isolates applying EUCAST over CLSI breakpoints
(Taylor & Francis Ltd, 2023)
BackgroundCefiderocol is generally active against carbapenem-resistant Klebsiella spp. (CRK) with higher MICs against metallo-beta-lactamase producers. There is a variation in cefiderocol interpretive criteria determined ...
Adipose-derived mesenchymal stem cells mitigate methotrexate-induced liver cirrhosis (fibrosis) model
(Verduci Editore s.r.l, 2023)
OBJECTIVE: Hepatic fibrosis is a severe liver condition characterized by abnormal fibroblast activity, excessive extracellular matrix deposition, inflammation, and structural alterations. Methotrexate (MTX), a pharmaceutical ...
Investigation of Neuroprotective Effect of Shilajit Extract in Experimental Head Trauma Model Created in Rats
(Turkish Neurosurgical Society, 2023)
AIM: To investigate the neuroprotective effect of shilajit extract in experimental head trauma. MATERIAL and METHODS: Three groups of 33 Sprague Dawley Albino strain male rats were included in the study. Group 1 (n=11): ...
MCM-2 Levels as a Potential Biomarker for Predicting High-Risk Breast Cancer Patients According to TAILORx Classification
(Dove Medical Press Ltd, 2023)
Background: The minichromosome maintenance protein-2 (MCM-2) is a more sensitive proliferation marker than Ki-67. This study aimed to evaluate the relationship between MCM-2 and Oncotype DX recurrence score (ODX-RS) and ...
Evaluation of Atherosclerotic Risk by Oxidative Contributors in Alcohol Use Disorder
(Korean Coll Neuropsychopharmacology, 2023)
Objective: Alcohol Use Disorder (AUD) is a condition described as the inability to control or stop alcohol consumption. The patients with AUD have an increased risk of developing atherosclerosis-related diseases. The present ...
Anti-inflammatory and antioxidant properties of betaine protect against sepsis-induced acute lung injury: CT and histological evidence
(Assoc Bras Divulg Cientifica, 2023)
The aim of this research was to determine the anti-inflammatory effect of betaine on sepsis-induced acute respiratory distress syndrome (ARDS) in rats through histopathological examination, radiologic imaging, and biochemical ...
High prevalence of ArmA-16S rRNA methyltransferase among aminoglycoside-resistant Klebsiella pneumoniae bloodstream isolates
(Microbiology Society, 2022)
Introduction. Aminoglycosides are used for the treatment of carbapenemase-producing Klebsiella pneumoniae (CPK) infections. 16S rRNA methyltransferases (RMTs) confer resistance to all aminoglycosides and are often cocarried ...
Prognostic Factors in Patients with Clinic Locally Advanced T4 Lung Cancer: Surgical Considerations
(Georg Thieme Verlag, 2022)
Background Inclusion of surgery in the treatment of T4 lung cancer has been a debate for the last two decades. The aim of this study is to investigate the potential prognostic factors which could affect the outcome. Methods ...