Güncel Gönderiler: PubMed İndeksli Yayınlar Koleksiyonu
Toplam kayıt 1613, listelenen: 41-60
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Expanding the genotypic spectrum of 3β-hydroxy-δ5-C27-steroid dehydrogenase (HSD3B7) deficiency: novel mutations and clinical outcomes
(Walter De Gruyter Gmbh, 2025)Objectives: HSD3B7 deficiency is a genetic disorder caused by mutations in the HSD3B7 gene, leading to impaired bile acid synthesis and the accumulation of toxic intermediates. Affected patients typically present with ... -
Evaluating Risk in Kidney Living Donors
(Frontiers Media Sa, 2025)Kidney donation is a safe procedure for carefully screened donors. The growing shortage of organs and improved survival rates among recipients of living donor transplants have broadened the criteria for acceptable living ... -
Thematic Review of Endocrine Disruptors and Their Role in Shaping Pubertal Timing
(Mdpi, 2025)This review examines the inconsistent effects of endocrine-disrupting chemicals (EDCs) and pollutants on pubertal timing, emphasizing the methodological challenges contributing to variability in findings. Data from nine ... -
Success: the synergy of off-pump coronary artery bypass and living donor liver transplantation-a two-case report
(Frontiers Media Sa, 2025)Background End-stage liver disease (ESLD) patients frequently exhibit comorbid coronary artery disease (CAD), complicating liver transplantation (LT) due to increased perioperative cardiovascular risk. In patients for whom ... -
Caffeine use in preterm neonates: national insights into Turkish NICU practices
(Frontiers Media Sa, 2025)Objective: Caffeine is a proven medication used for the prevention and treatment of apnea in premature infants, offering both short- and long-term benefits. International guidelines provide a range of recommendations ... -
Severe Lipoatrophy in a Growth Hormone Deficient Toddler Girl Treated with a Non-Pegylated Long-Acting Growth Hormone
(Mdpi, 2025)Background: Recombinant growth hormone (rhGH) has been used since 1985 to treat growth hormone (GH)-induced short stature, typically associated with transient adverse events. However, lipoatrophy, characterized by irreversible ... -
Methylene Blue Alleviates Inflammatory and Oxidative Lung Injury in a Rat Model of Feces-Induced Peritonitis
(Mdpi, 2025)Background and Objectives: Feces-induced peritonitis (FIP), a clinically relevant model of polymicrobial sepsis, induces systemic inflammation and acute lung injury (ALI). Methylene blue (MB), a phenothiazine-based compound, ... -
Prognostic Role of Inflammatory and Nutritional Indices in NSCLC Patients Treated with Immune Checkpoint Inhibitors: Retrospective, Multicenter, Turkish Oncology Group Study of Overall and Elderly Populations
(Mdpi, 2025)Background and Objectives: Despite advances in immunotherapy, predicting survival outcomes in patients with non-small-cell lung cancer (NSCLC) remains challenging. Inflammatory and nutritional indices such as the Prognostic ... -
Anti-glioma effect of Turkish propolis in C6 cells via regulation of COX-2 and NF-κB mRNA expression and redox homeostasis
(Univ Karachi, 2024)This study aims to determine whether Turkish propolis applied to C6 glioma cells has an anti-glioma effect. To investigate this, C6 glioma cells were treated with propolis extract concentrations of 100, 250, and 500 mu ... -
Ivermectin Attenuates Methotrexate-Induced Liver Fibrosis by Reducing TGF-β and Syndecan-1 Expression
(Mdpi, 2025)Background and Objectives: Methotrexate (MTX) is widely used in clinical settings but is often associated with hepatotoxic side effects, including oxidative stress, inflammation, and fibrosis. Novel therapeutic strategies ... -
Assessing Psychosocial Burden in Psoriasis Patients Using the PRISM-RII Tool: A Comprehensive Evaluation
(Mattioli 1885, 2025)Introduction: Psoriasis is a chronic, immune-mediated inflammatory disease that significantly impacts patients' quality of life due to its visible lesions and associated stigma. Psychological comorbidities are prevalent ... -
Investigation of the Potential Effect of Complement 5 on Transplantation Outcome by Bioinformatics Tools
(Iranian Soc Nephrolgy, 2025)Introduction. Activation of the complement system following transplantation may result in allograft rejection. Our study aimed to evaluate the potential relationship between factors affecting kidney transplant success and ... -
Adult disability assessment in Türkiye with real-life experiences of physiatrists: A cross-sectional analytic study
(Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2025)Objectives: The aim of this study was to determine the workload and problems of physiatrists in disability assessment in T & uuml;rkiye. Materials and methods: A 39-question electronic survey was administered between May ... -
Intraoperative Neurophysiologic Monitoring Improves Neurologic Outcomes in Eloquent Brain Areas and Aids in Increasing the Volume of Resected Glioma: Current Results Compared With Historical Controls
(Lippincott Williams and Wilkins, 2025)Purpose: This study aims to show the impact of multimodal intraoperative neurophysiologic monitoring (IOM) in glioma surgery in preventing severe neurologic injury and increasing tumor removal by comparing the historical ... -
Investigation of the protective effects of dichloroacetic acid in a rat model of diabetic neuropathy
(BioMed Central Ltd, 2025)Background: Diabetic neuropathy (DN) is a heterogeneous condition characterized by complex pathophysiological changes affecting both autonomic and somatic components of the nervous system. Inflammation and oxidative stress ... -
Hippo signaling pathway in human testis and seminoma: anticancer effect of verteporfin on human seminoma TCam-2 cells
(Springer Science and Business Media B.V., 2025)Aim: Seminoma and embryonal carcinoma are among the most common germ cell tumors. Verteporfin, a YAP-TEAD inhibitor, has emerged as a potential anticancer agent. This study investigated the localization of Hippo signaling ... -
Rejuvenating the gut: young plasma therapy improves cell proliferation, IGF-I and IGF-IR expression, and immune defense in aged male rats jejunum
(Springer Science and Business Media B.V., 2025)It is well known that aging affects many systems in the body. The digestive system is one of the systems most affected by aging. In our study, we examined the effects of young plasma treatment on cell proliferation, growth ... -
Invited Response on: Comment on ‘‘The Impact of Duration and Force of Centrifugation on Platelet Content and Mass in the Preparation of Platelet-Rich Plasma’’
(Springer, 2025)Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online ... -
De-Escalation of Nodal Surgery in Clinically Node-Positive Breast Cancer
(American Medical Association, 2025)Importance: Increasing evidence supports the oncologic safety of de-escalating axillary surgery for patients with breast cancer after neoadjuvant chemotherapy (NAC). Objective: To evaluate the oncologic outcomes of ...
