Evaluation of carotid intima media thickness in early onset androgenetic alopesia [Erken başlangıçlı androgenetik alopeside karotis intima kalınlığının değerlendirilmesi]

Abstract

Purpose of this study was to evaluate of carotid intima- media thickness (CIMT) together with biochemical parameters in male patients with early-onset androgenetic alopecia (AGA) without risk factors for cardiovascular disease and to reveal the relationship between early-onset AGA and cardiac arrhythmia, atherosclerosis, metabolic syndrome in patients with P wave and QT dispersion in electrocardiography. Forty men with early onset AGA and 50 healthy men without AGA in the age group of 18-35 years were included in this study.We compared the biochemical values, blood pressure, carotid intima- media thickness (CIMT), echocardiographic(echo) and electrocardiographic (ECG) parameters. the mean age was 28.03±4.95/years and the mean CIMT was 0.63±0.12 cm in the group with early onset AGA. the mean age was 28.95±5.03 /years and the mean CIMT was 0.51±0.1 cm in the control group. CIMT was correlated with AGA (p<0.05). the mean HOMA-IR (Homeostatic Model Assessment-Insulin Re-sistance) index was 2.35±1.97 in the patient group and 1.85±1.65 in the healthy group . HOMA-IR is related with early onset AGA (p<0.05). on the other hand, echo and ECG parameters were not correlated with early onset AGA. the relationship between CIMT, HOMA-IR and early onset AGA may indicate that premature atherosclerosis is present in these patients. However, since clinical conditions of atherosclerosis may appear in the early onset AGA, appropriate screening methods should be used. © 2018, Logos Medical Publishing. All rights reserved.