An atypical acute exacerbation of COPD due to Aspergillus fumigatus
dc.contributor.author | Tetikkurt, C. | |
dc.contributor.author | Kubat, B. | |
dc.contributor.author | Tetikkurt, S. | |
dc.contributor.author | Karakas, G. | |
dc.date.accessioned | 2020-12-02T18:00:11Z | |
dc.date.available | 2020-12-02T18:00:11Z | |
dc.date.issued | 2020 | |
dc.identifier.issn | 1122-0643 | |
dc.identifier.uri | https://doi.org/10.4081/monaldi.2020.1155 | |
dc.identifier.uri | http://hdl.handle.net/11446/3555 | |
dc.description | PubMed: 31986874 | en_US |
dc.description.abstract | A 64-year-old male with a history of stabile chronic obstructive pulmonary disease (COPD) presented with increasing dyspnea and sputum for the last two months. Complete blood count showed WBC 14x103/ml, Hgb: 14.2 g/dL and eosinophilia. Blood biochemistry was normal. Chest x-ray showed hyperlucency while thorax computed tomography (CT) revealed obstructive lung disease and bronchiectasis. Pulmonary function tests demonstrated severe obstructive lung disease and a negative bronchoreversibility with a moderately reduced diffusing capacity/alveolar volume (DLCO/VA). ABG gases revealed significant hypoxemia. Sputum culture was negative. Total IgE was 1140 ng/ml. Aspergillus RAST, precipitins and aspergillus-galactomannan antigen were positive. CF genetic screening tests gave negative results. Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity reaction that occurs due to bronchial aspergillus colonization. It is most common in patients with asthma and cystic fibrosis. We present a COPD case with an acute exacerbation due to Aspergillus fumigatus that lead to an aberrant clinical profile unresponsive to conventional treatment. Clinicians should consider Aspergillus fumigatus as an etiologic agent in an atypical and severe COPD exacerbation. © Copyright the Author(s), 2020 Licensee PAGEPress, Italy | en_US |
dc.language.iso | eng | en_US |
dc.publisher | PAGEPress Publications | en_US |
dc.identifier.doi | 10.4081/monaldi.2020.1155 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | ABPA | en_US |
dc.subject | Aspergillus fumigatus | en_US |
dc.subject | COPD | en_US |
dc.subject | COPD acute exacerbation | en_US |
dc.title | An atypical acute exacerbation of COPD due to Aspergillus fumigatus | en_US |
dc.type | article | en_US |
dc.relation.journal | Monaldi Archives for Chest Disease | en_US |
dc.department | DBÜ | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.volume | 90 | en_US |
dc.identifier.startpage | 13 | en_US |
dc.identifier.endpage | 16 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.department-temp | Tetikkurt, C., Department of Pulmonary Medicine, Cerrahpasa Medical Faculty, Istanbul Cerrahpasa University, Istanbul, Turkey; Kubat, B., Department of Pulmonary Medicine, Cerrahpasa Medical Faculty, Istanbul Cerrahpasa University, Istanbul, Turkey; Tetikkurt, S., Pathology Department, Florence Nightingale Hospital, Demiroglu Bilim University, Istanbul, Turkey; Karakas, G., Department of Pulmonary Medicine, Cerrahpasa Medical Faculty, Istanbul Cerrahpasa University, Istanbul, Turkey | en_US |
Bu öğenin dosyaları:
Dosyalar | Boyut | Biçim | Göster |
---|---|---|---|
Bu öğe ile ilişkili dosya yok. |
Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.
-
PubMed İndeksli Yayınlar Koleksiyonu [1488]
PubMed Indexed Publications Collection -
Scopus İndeksli Yayınlar Koleksiyonu [1747]
Scopus Indexed Publications Collection -
WoS İndeksli Yayınlar Koleksiyonu [2110]
WoS Indexed Publications Collection