Perirhinal cortical kindling in genetic absence epilepsy rat strains
Künye
Akman O, Karson A, Ates N, Onat F. Perirhinal Cortical Kindling In Genetic Absence Epilepsy Rat Strains. Epilepsia. 2010; 51(Suppl 4):1–189. 9th European Congress on Epileptology, Rhodes, Greece, 27 June–1 July 2010 doi: 10.1111/j.1528-1167.2010.02658.xÖzet
Purpose: The genetic models of absence epilepsy, GAERS and WAG/ Rij rat strains, are resistant to progression of partial seizures induced by amygdaloid and hippocampal kindling. Perirhinal cortex is a crucial area for the secondary generalization of partial seizures. Kindling epileptogeniticy is propagated from perirhinal cortex to other areas that are responsible for generalized seizures. Therefore we focused on perirhinal cortical kindling in both epileptic rat strains and compared them with Wistar rats.
