The management of renal candidiasis in a newborn infant with posterior urethral valve

Abstract

Renal candidiasis with fungal bezoars in the newborn infant is rarely encountered. We report a newborn with renal candidiasis and posterior uretral valve treated by local irrigation of the kidneys (three weeks) with amphotericin B via percutaneously inserted nephrostomy catheter, in combination with intravenous flucanazol (four weeks). Renal function subsequently improved and fungal bezoars disappeared sonographically. No side effects were observed during the follow up. We suggest that local irrigation with amphotericin B in combination with systemic flucanazol may be the initial treatment of renal candidiasis, aiming at both the restoration of renal function and the eradication of the fungal infection.