dc.contributor.author | Mercan, S. | |
dc.contributor.author | Vehid, H. | |
dc.contributor.author | Semen, S. | |
dc.contributor.author | Celik, U. | |
dc.contributor.author | Yayla, M. | |
dc.contributor.author | Engin, B. | |
dc.date.accessioned | 2021-06-10T19:38:14Z | |
dc.date.available | 2021-06-10T19:38:14Z | |
dc.date.issued | 2021 | |
dc.identifier.issn | 0163-4984 | |
dc.identifier.uri | https://doi.org/10.1007/s12011-021-02636-y | |
dc.identifier.uri | http://hdl.handle.net/11446/4255 | |
dc.description | 2-s2.0-85101220780 | en_US |
dc.description.abstract | Nickel (Ni) is a frequently used metal in the production of many products, and Ni exposure occurs in humans through food, inhalation, and skin. Studies reported Ni as the most common allergen diagnosed in the serial patch test. The main purpose of our study was to determine the concentration of Ni and other elements in the urine samples of individuals with Ni-sensitivity and to determine the effect of lifestyle habits on these variables. This study was conducted with 388 participants; additionally, both Ni patch test and inorganic analysis (for 24 elements) method in urine with inductively coupled plasma-mass spectrometry (ICP-MS) were applied to all participants. Ninety-two (23.7%) of the participants were found to have nickel sensitivity with a mean urine concentration of 4.475 ?g/g creatinine (median=4.260; SD=2.527). The urine nickel concentration was significantly different between female and male participants (p =0.001). We found a significant correlation between Ni and other metals alongside various element pairs. The mean urine Ni concentration of the individuals with a positive Ni sensitivity test result was not different from that of the participants without Ni sensitivity (4.475 vs 4.256 ?g/g creatinine, respectively; p = 0.068). The high accuracy, recovery, and repeatability data obtained from the analyses indicate that this study is efficient and appropriate for the quantitative determination of nickel and other elements in urine samples. Ni-containing objects and Ni-rich foods should be of concern for individuals with hypersensitivity reactions to the element. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature. | en_US |
dc.description.sponsorship | 213S098, BYP-54488 Türkiye Bilimsel ve Teknolojik Araştirma Kurumu, TÜBITAK | en_US |
dc.description.sponsorship | Authors would like to thank the Scientific and Technological Research Council of Turkey (TUBITAK) and Scientific Research Fund of Istanbul University-Cerrahpaşa, Turkey, for support of this work with the Project numbers 213S098 and BYP-54488, respectively. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Humana Press Inc. | en_US |
dc.identifier.doi | 10.1007/s12011-021-02636-y | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Contact dermatitis | en_US |
dc.subject | ICP-MS | en_US |
dc.subject | Imitation jewelry | en_US |
dc.subject | Nickel | en_US |
dc.subject | Occupational exposure | en_US |
dc.title | An ICP-MS Study for Quantitation of Nickel and Other Inorganic Elements in Urine Samples: Correlation of Patch Test Results with Lifestyle Habits | en_US |
dc.type | article | en_US |
dc.relation.journal | Biological Trace Element Research | en_US |
dc.department | [0-Belirlenecek] | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.institutionauthor | [0-Belirlenecek] | |
dc.department-temp | Mercan, S., Institute of Forensic Sciences and Legal Medicine, Department of Science, Istanbul University–Cerrahpaşa, Buyukcekmece, Istanbul, 34500, Turkey; Vehid, H., Department of Medical Training and Informatics, Istanbul Demiroglu Bilim University, Sisli, Istanbul, 34394, Turkey; Semen, S., Institute of Forensic Sciences and Legal Medicine, Department of Science, Istanbul University–Cerrahpaşa, Buyukcekmece, Istanbul, 34500, Turkey; Celik, U., Cerrahpasa Medical Faculty, Department of Dermatology and Venerology, Istanbul University–Cerrahpaşa, Istanbul, 34098, Turkey; Yayla, M., Institute of Forensic Sciences and Legal Medicine, Department of Science, Istanbul University–Cerrahpaşa, Buyukcekmece, Istanbul, 34500, Turkey; Engin, B., Cerrahpasa Medical Faculty, Department of Dermatology and Venerology, Istanbul University–Cerrahpaşa, Istanbul, 34098, Turkey | en_US |