dc.contributor.author | Hot, Semih | |
dc.contributor.author | Egin, Seracettin | |
dc.contributor.author | Ilhan, Mehmet | |
dc.contributor.author | Bademler, Suleyman | |
dc.contributor.author | Dikker, Okan | |
dc.contributor.author | Aciksari, Kurtulus | |
dc.contributor.author | Kamali, Gulcin | |
dc.date.accessioned | 2021-06-10T19:38:39Z | |
dc.date.available | 2021-06-10T19:38:39Z | |
dc.date.issued | 2021 | |
dc.identifier.issn | 1734-1922 | |
dc.identifier.issn | 1896-9151 | |
dc.identifier.uri | https://doi.oeg/10.5114/aoms.2019.84225 | |
dc.identifier.uri | http://hdl.handle.net/11446/4397 | |
dc.description | egin, seracettin/0000-0002-4090-5205 | en_US |
dc.description | PubMed: 33488876 | en_US |
dc.description | WOS:000615581000028 | en_US |
dc.description.abstract | Introduction: The aim of this randomized controlled experimental study was to evaluate the efficacy of potassium, pH and D-dimer levels in blood, as well as potassium and pH levels in peritoneal lavage fluid, in the early diagnosis of acute mesenteric ischemia. Material and methods: This study was conducted at the Istanbul University Center of Experimental Medicine after having received approval from the Istanbul University animal testing ethics committee. Male albino Wistar rats (n = 24; 250 to 350 g) were divided into two control groups and two ischemic groups. Levels of potassium, pH, and D-dimer in blood and levels of potassium and pH in peritoneal lavage fluid were analyzed for 1 h and 2 h after the induced acute mesenteric ischemia procedure. The degree of ischemic injury was determined using the histopathological damage score in tissue samples taken from the terminal ileum. Results: Ischemic groups had statistically significant differences in potassium and pH in blood and peritoneal lavage fluid compared to non-ischemic groups (p < 0.05). There was no significant difference between control and ischemic groups in terms of D-dimer and histologic grading results after 1 h (p = 0.132, p = 0.475 respectively), while there was a significant difference between control and ischemic groups after 2 h (p < 0.05). Conclusions: The levels of potassium, pH, and D-dimer could be useful in daily practice for the early diagnosis of acute mesenteric ischemia. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Termedia Publishing House Ltd | en_US |
dc.identifier.doi | 10.5114/aoms.2019.84225 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | pH | en_US |
dc.subject | potassium | en_US |
dc.subject | D-dimer | en_US |
dc.subject | acute mesenteric ischemia | en_US |
dc.title | The value of potassium, pH and D-dimer levels in early diagnosis of acute mesenteric ischemia: an experimental study on rats | en_US |
dc.type | article | en_US |
dc.relation.journal | Archives Of Medical Science | en_US |
dc.department | [0-Belirlenecek] | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.volume | 17 | en_US |
dc.identifier.startpage | 236 | en_US |
dc.identifier.endpage | 240 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.institutionauthor | [0-Belirlenecek] | |
dc.department-temp | [Hot, Semih; Egin, Seracettin; Kamali, Sedat] Univ Hlth Sci, Okmeydan Educ Res Hosp, Dept Gen Surg, Istanbul, Turkey; [Ilhan, Mehmet; Bademler, Suleyman; Guloglu, Recep] Istanbul Univ, Istanbul Fac Med, Dept Gen Surg, Istanbul, Turkey; [Dikker, Okan] Univ Hlth Sci, Okmeydan Educ Res Hosp, Dept Biochem, Istanbul, Turkey; [Aciksari, Kurtulus] Istanbul Bilim Univ, Fac Med, Dept Emergency Med, Istanbul, Turkey; [Kamali, Gulcin] Univ Hlth Sci, Okmeydan Educ Res Hosp, Dept Pathol, Istanbul, Turkey; [Seckin, Ismail; Tanriverdi, Gamze] Istanbul Univ, Cerrahpasa Fac Med, Dept Histol & Embryol, Istanbul, Turkey | en_US |