Effects of curcumin intake on fatty liver in high fat diet fed rats

Abstract

Background: Long term high fat diet (HFD) intake causes lots of metabolic disorders and a major risk factor for nonalcoholic fatty liver. Curcumin (Cur) is a well-known compound of traditional turmeric "Curcuma longa" which has been shown to display antioxidative, anticarcinogenic, anti-inflammatory and hypocholesterolemic effects, The aim of this study was to evaluate the effects of curcumin treatment on liver fat accumulation and prooxidant-antioxidant status in an experimental high-fat diet fed rat model.