dc.contributor.author | Kockar, A. | |
dc.contributor.author | Gün, R.D. | |
dc.contributor.author | Temizsoylu, O. | |
dc.contributor.author | Sengul, E.A. | |
dc.contributor.author | Alataş, İ. | |
dc.contributor.author | Yüzbaşıoğlu, E. | |
dc.date.accessioned | 2022-11-04T19:55:43Z | |
dc.date.available | 2022-11-04T19:55:43Z | |
dc.date.issued | 2022 | |
dc.identifier.issn | 1572-1000 | |
dc.identifier.uri | https://doi.org/10.1016/j.pdpdt.2022.103125 | |
dc.identifier.uri | http://hdl.handle.net/11446/4613 | |
dc.description.abstract | Purpose: Spina bifida (SB) is a congenital disorder caused by the incomplete fusion of the embryonic neural tube during spinal cord development. In this study, we used Spectral Domain Optic Coherence Tomography (SD-OCT) for retinal nerve fibre layer (RNFL) and ganglion cell complex (GCC) analyses and compared the results of healthy children and SB patients in a similar age group. Methods: Our study was planned prospectively and conducted between June 2017 and July 2019. One hundred eyes of 50 participants, consisting of 28 SB patients and 22 healthy children were included. In all cases, RNFL and GCC measurements were undertaken using SD-OCT. The circumpapillary RNFL analysis was conducted by examining the circular area of 3.45 mm in diameter around the centre of the optic disc. GCC parameters were determined with MM7 protocols by taking 15 vertical sections from a 7-mm macular square centred in the fovea. Results: The mean GCC thickness of the participants was 91.120 ± 5.224 µm in the control group and 91.696 ± 7.410 µm in the SB group. The difference between the two groups was not statistically significant (p > 0.05). The mean RNFL thickness was 102.499 ± 11.250 µm in the control group and 99.549 ± 15.235 µm in the SB group. The mean RNFL thickness of the patients in the SB group was lower than that of the control group, but the difference was not statistically significant (p > 0.05). Conclusions: In this study, the lack of a statistically significant difference in the RNFL and GCC values between the SB and control groups can be attributed to successful clinical management. © 2022 | en_US |
dc.description.sponsorship | The author(s) received no financial support for the research, authorship, and/or publication of this article. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier B.V. | en_US |
dc.relation.ispartof | Photodiagnosis and Photodynamic Therapy | en_US |
dc.identifier.doi | 10.1016/j.pdpdt.2022.103125 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Ganglion cell complex | en_US |
dc.subject | Retinal nerve fibre layer spina bifida, Spectral domain optic coherence tomography | en_US |
dc.subject | anterior eye segment | en_US |
dc.subject | Article | en_US |
dc.subject | biomicroscopy | en_US |
dc.subject | child | en_US |
dc.subject | clinical article | en_US |
dc.subject | clinical study | en_US |
dc.subject | comparative study | en_US |
dc.subject | controlled study | en_US |
dc.subject | eye examination | en_US |
dc.subject | female | en_US |
dc.subject | ganglion cell complex | en_US |
dc.subject | human | en_US |
dc.subject | human cell | en_US |
dc.subject | intraocular pressure | en_US |
dc.subject | male | en_US |
dc.subject | optic disk | en_US |
dc.subject | retina ganglion cell | en_US |
dc.subject | retinal nerve fiber layer | en_US |
dc.subject | retinal nerve fiber layer thickness | en_US |
dc.subject | school child | en_US |
dc.subject | spectral domain optical coherence tomography | en_US |
dc.subject | spinal dysraphism | en_US |
dc.subject | visual acuity | en_US |
dc.title | Evaluation of ganglion cell complex and retinal nerve fiber layer in children with spina bifida using optical coherence tomography | en_US |
dc.type | article | en_US |
dc.identifier.volume | 40 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.department-temp | Kockar, A., Ümraniye Training and Research Hospital Ophthalmology Department, Turkey; Gün, R.D., Kartal Lütfi Kırdar Training and Research Hospital Ophthalmology Department, Turkey; Temizsoylu, O., Moorfields Eye Hospital, United Kingdom; Sengul, E.A., T.C. Istanbul Demiroğlu Bilim University Medical Faculty Ophthalmology Department, Turkey; Alataş, İ., T.C. Istanbul Demiroğlu Bilim University Medical Faculty Neurosurgery Department, Turkey; Yüzbaşıoğlu, E., T.C. Istanbul Demiroğlu Bilim University Medical Faculty Ophthalmology Department, Turkey | en_US |
dc.identifier.pmid | 36126829 | en_US |
dc.identifier.scopus | 2-s2.0-85139300857 | en_US |
dc.authorscopusid | 57189257633 | |
dc.authorscopusid | 57678985100 | |
dc.authorscopusid | 56083674200 | |
dc.authorscopusid | 25026450300 | |
dc.authorscopusid | 8715879500 | |
dc.authorscopusid | 12764175600 | |