dc.contributor.author | Yilmaz, M. Temel | |
dc.contributor.author | Caklili, Ozge Telci | |
dc.contributor.author | Hacisahinogullari, Hulya | |
dc.contributor.author | Cakmak, Ramazan | |
dc.contributor.author | Sahiner, Elif | |
dc.contributor.author | Keskin, Ela | |
dc.date.accessioned | 2024-02-04T13:29:34Z | |
dc.date.available | 2024-02-04T13:29:34Z | |
dc.date.issued | 2023 | |
dc.identifier.issn | 2822-6135 | |
dc.identifier.uri | https://doi.org/10.5152/erp.2023.22130175 | |
dc.identifier.uri | https://search.trdizin.gov.tr/yayin/detay/1178936 | |
dc.identifier.uri | http://hdl.handle.net/11446/4683 | |
dc.description.abstract | Objective: The conventional approach to brittle diabetes is the treatment of underlying causes and optimization with multiple-dose insulin injections. The goal of multiple- dose insulin therapy is to exactly mimic physiological insulin secretion; however, it often results in hypoglycemia. This study investigates the effectiveness of continuous subcutaneous insulin infusion therapy with a patch pump with the sensor augmented with predictive low- glucose suspend algorithm system in patients with uncontrolled type 1 diabetes who were treated with multiple-dose insulin and have high glycated hemoglobin values. Methods: The data of patients whose glycemic control could not be achieved with multiple-dose insulin therapy and who were switched to sensor-augmented tubeless pump with predictive lowglucose suspend feature (Medtrum A7+ TouchCare patch pump and integrated A7+ continuous glucose monitoring system) were analyzed retrospectively. Results: A total of 16 patients (male: 9; 56.3%) were included. After 3 months of the sensor-augmented pump with predictive low-glucose suspend treatment, patients'median (interquartile range) glycated hemoglobin level decreased to 7.55 (1.43) from 9.20 (3.55) (P =.008). Time below 56 mg/dL was 0.34%, time between 56 and 70 mg/dL was 1.01%, time between 70 and 180 mg/dL was 72.90%, time above 180 mg/dL was 25.67%, time between 70and 250 mg/dL was 95.98%, and time above 250 mg/dL was 2.76%. Conclusions: A pump system with predictive low-glucose suspend feature improves glycemic targets in patients with brittle uncontrolled type 1 diabetes without the expense of hypoglycemia compared to multiple-dose insulin treatment. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Aves | en_US |
dc.relation.ispartof | Endocrinology Research And Practice | en_US |
dc.identifier.doi | 10.5152/erp.2023.22130175 | |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Predictive low-glucose suspend | en_US |
dc.subject | multiple | en_US |
dc.subject | dose insulin | en_US |
dc.subject | brittle diabetes | en_US |
dc.title | Effect of Sensor-Augmented Patch Pump with Predictive Low-Glucose Suspend Feature Compared to Multiple-Dose Insulin in Patients with Brittle Type 1 Diabetes | en_US |
dc.type | article | en_US |
dc.department | DBÜ | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.volume | 27 | en_US |
dc.identifier.startpage | 44 | en_US |
dc.identifier.endpage | 47 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.department-temp | [Yilmaz, M. Temel; Keskin, Ela] Demiroglu Bilim Univ, Dept Endocrinol & Metab, Istanbul, Turkiye; [Caklili, Ozge Telci; Hacisahinogullari, Hulya] Istanbul Univ, Dept Endocrinol & Metab, Fac Med, Istanbul, Turkiye; [Hacisahinogullari, Hulya] Med Pk Hosp Gaziosmanpasa, Dept Endocrinol & Metab, Istanbul, Turkiye; [Sahiner, Elif] Hacettepe Univ, Dept Nutr & Dietet, Fac Med, Ankara, Turkiye | en_US |
dc.identifier.scopus | 2-s2.0-85159913633 | en_US |
dc.identifier.wos | WOS:001110296900002 | en_US |
dc.identifier.trdizinid | 1178936 | en_US |