dc.contributor.author | Yildirim, Halil Cumhur | |
dc.contributor.author | Kupik, Gulnihan Eren | |
dc.contributor.author | Mustafayev, Teuta Zoto | |
dc.contributor.author | Berber, Tanju | |
dc.contributor.author | Yavuz, Berrin | |
dc.contributor.author | Cetinayak, Oguz | |
dc.contributor.author | Akagunduz, Ozlem | |
dc.date.accessioned | 2024-02-04T13:29:35Z | |
dc.date.available | 2024-02-04T13:29:35Z | |
dc.date.issued | 2023 | |
dc.identifier.issn | 1043-3074 | |
dc.identifier.issn | 1097-0347 | |
dc.identifier.uri | https://doi.org/10.1002/hed.27333 | |
dc.identifier.uri | http://hdl.handle.net/11446/4691 | |
dc.description.abstract | BackgroundWe aimed to evaluate patients with nasopharyngeal carcinoma (NPC) in a nonendemic population. MethodsIn a national, retrospective, multicenteric study, 563 patients treated with intensity modulated radiotherapy at 22 centers between 2015 and 2020 were analyzed. ResultsMedian age was 48 (9-83), age distribution was bimodal, 74.1% were male, and 78.7% were stage III-IVA. Keratinizing and undifferentiated carcinoma rates were 3.9% and 81.2%. Patients were treated with concomitant chemoradiotherapy (48.9%), or radiotherapy combined with induction chemotherapy (25%) or adjuvant chemotherapy (19.5%). After 34 (6-78) months follow-up, 8.2% locoregional and 8% distant relapse were observed. Three-year overall survival was 89.5% and was lower in patients with age >= 50, male sex, keratinizing histology, T4, N3 and advanced stage (III-IVA). ConclusionsPatients with NPC in Turkey have mixed clinical features of both east and west. Survival outcomes are comparable to other reported series; however, the rate of distant metastases seems to be lower. | en_US |
dc.description.sponsorship | University Grants Commission (UGC), New Delhi [8- 4(57)/2015(MRP/NRCB]; UGC-DAE CSR Kolkata Centre | en_US |
dc.description.sponsorship | The author, Ashok K. Pathak, acknowledges financial assistance from the University Grants Commission (UGC), New Delhi (8- 4(57)/2015(MRP/NRCB)). Author, V. K. Singh is very thankful to UGC-DAE CSR Kolkata Centre for partial financial support. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Wiley | en_US |
dc.relation.ispartof | Head And Neck-Journal For The Sciences And Specialties Of The Head And Neck | en_US |
dc.identifier.doi | 10.1002/hed.27333 | |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | chemoradiotherapy | en_US |
dc.subject | EBV-DNA | en_US |
dc.subject | intensity-modulated radiotherapy | en_US |
dc.subject | nasopharyngeal carcinoma | en_US |
dc.subject | nonendemic | en_US |
dc.title | A multicenter retrospective analysis of patients with nasopharyngeal carcinoma treated in IMRT era from a nonendemic population: Turkish Society for Radiation Oncology Head and Neck Cancer Group Study (TROD 01-001) | en_US |
dc.type | article | en_US |
dc.department | DBÜ | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.volume | 45 | en_US |
dc.identifier.startpage | 1194 | en_US |
dc.identifier.endpage | 1205 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.department-temp | [Yildirim, Halil Cumhur] Istanbul Univ Cerrahpasa, Cerrahpasa Fac Med, Dept Radiat Oncol, Istanbul, Turkiye; [Kupik, Gulnihan Eren] Mugla Sitki Kocman Univ, Fac Med, Dept Radiat Oncol, Mugla, Turkiye; [Mustafayev, Teuta Zoto; Ozyar, Enis] Acibadem Univ, Fac Med, Dept Radiat Oncol, Istanbul, Turkiye; [Berber, Tanju] Prof Dr Cemil Tascioglu City Hosp, Dept Radiat Oncol, Istanbul, Turkiye; [Yavuz, Berrin] Necmettin Erbakan Univ, Meram Fac Med, Dept Radiat Oncol, Konya, Turkiye; [Cetinayak, Oguz; Akman, Fadime] Dokuz Eylul Univ, Fac Med, Dept Radiat Oncol, Izmir, Turkiye; [Akagunduz, Ozlem] Ege Univ, Fac Med, Dept Radiat Oncol, Izmir, Turkiye; [Bicakci, Beyhan Ceylaner] Kartal Dr Lutfi Kirdar City Hosp, Dept Radiat Oncol, Istanbul, Turkiye; [Arslan, Suheyla Aytac] Ankara City Hosp, Dept Radiat Oncol, Ankara, Turkiye; [Soykut, Ela Delikgoz] Samsun Educ & Res Hosp, Dept Radiat Oncol, Samsun, Turkiye; [Gundog, Mete] Erciyes Univ, Fac Med, Dept Radiat Oncol, Kayseri, Turkiye; [Figen, Metin] Sisli Hamidiye Etfal Educ & Res Hosp, Dept Radiat Oncol, Istanbul, Turkiye; [Teke, Fatma] Dicle Univ, Fac Med, Dept Radiat Oncol, Diyarbakir, Turkiye; [Canyilmaz, Emine] Karadeniz Tech Univ, Fac Med, Dept Radiat Oncol, Trabzon, Turkiye; [Birgi, Sumerya Duru] Ankara Univ, Fac Med, Dept Radiat Oncol, Ankara, Turkiye; [Duzova, Mursel] Selcuk Univ, Fac M | en_US |
dc.authorid | ceylaner bıçakcı, beyhan/0000-0003-2509-6742 | |
dc.authorid | Delikgoz Soykut, Ela/0000-0003-1225-8458 | |
dc.authorid | Çetinayak, Hasan Oğuz/0000-0002-8823-8341 | |
dc.authorid | Zoto Mustafayev, Teuta/0000-0001-6029-1995 | |
dc.authorid | Ozkaya Akagunduz, Ozlem/0000-0001-9733-774X | |
dc.authorid | HANEDAN USLU, Gonca/0000-0002-9722-9607 | |
dc.authorid | yildirim, halil cumhur/0000-0002-1412-1933 | |
dc.identifier.pmid | 36854873 | en_US |
dc.identifier.scopus | 2-s2.0-85149269238 | en_US |
dc.identifier.wos | WOS:000940768500001 | en_US |
dc.authorwosid | ceylaner bıçakcı, beyhan/HJH-5904-2023 | |
dc.authorwosid | Delikgoz Soykut, Ela/AEX-9110-2022 | |
dc.authorwosid | Çetinayak, Hasan Oğuz/AGH-4972-2022 | |