dc.contributor.author | Anilir, Ender | |
dc.contributor.author | Oral, Alihan | |
dc.contributor.author | Sahin, Tolga | |
dc.contributor.author | Turker, Fatih | |
dc.contributor.author | Yuzer, Yildiray | |
dc.contributor.author | Tokat, Yaman | |
dc.date.accessioned | 2024-02-04T13:29:48Z | |
dc.date.available | 2024-02-04T13:29:48Z | |
dc.date.issued | 2023 | |
dc.identifier.issn | 1307-5888 | |
dc.identifier.issn | 2757-7392 | |
dc.identifier.uri | https://doi.org/10.14744/hf.2022.2022.0037 | |
dc.identifier.uri | http://hdl.handle.net/11446/4753 | |
dc.description.abstract | Background and Aim: Combined hepatocellular-cholangiocarcinoma (CHC) requires attention clinically and pathologically after liver transplantation (LT) because of its unique biology, difficulties in diagnosis, and being rare. We aimed to present our single-center experience for this incidental combined tumor. It is aimed to present our single-center experience for this incidental combined tumor.Materials and Methods: Seventeen patients with CHC were included in the study. There were 260 hepatocellular carcinoma (HCC) patients deter-mined as the control group. Patients were evaluated for demographic, etiological, pathological features, and survival. Results: Macrovascular and microvascular invasion levels were significantly higher in the CHC group (p<0.05). P53, CK19, and CK7 levels were significantly higher in the CHC group (p<0.05). Hepatocyte-specific antigen level was significantly higher in the HCC group. The mean overall survival was significantly higher in the HCC group (p<0.05).Conclusion: Even though CHC is a rare liver tumor, it has features that need to be clarified regarding both survival and tumor biology. Investigating prognostic factors, especially in terms of survival and recurrence, will be very beneficial to identify candidates who will benefit from LT and be included in the indications for LT for CHC. This study evaluated the outcomes of patients showing combined HCC-intrahepatic cholangiocarcinoma in explant pathology. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Kare Publ | en_US |
dc.relation.ispartof | Hepatology Forum | en_US |
dc.identifier.doi | 10.14744/hf.2022.2022.0037 | |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Combined hepatocellular-cholangiocarcinoma | en_US |
dc.subject | incidental | en_US |
dc.subject | liver | en_US |
dc.subject | mixed tumor | en_US |
dc.subject | transplantation | en_US |
dc.title | Incidental combined hepatocellular-cholangiocarcinoma in liver transplant patients: Does it have a worse prognosis? | en_US |
dc.type | article | en_US |
dc.department | DBÜ | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.volume | 4 | en_US |
dc.identifier.startpage | 97 | en_US |
dc.identifier.endpage | 102 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.department-temp | [Anilir, Ender] Istanbul Aydin Univ, Medikalpark Florya Hosp, Organ Transplantat Ctr, Istanbul, Turkiye; [Oral, Alihan] Biruni Univ, Internal Med Ctr, Fac Med, Istanbul, Turkiye; [Sahin, Tolga] Demiroglu Bilim Univ, Grp Florence Nightingale Hosp, Dept Hepatol, Istanbul, Turkiye; [Sahin, Tolga; Yuzer, Yildiray] Demiroglu Bilim Univ, Grp Florence Nightingale Hosp, Liver Transplantat Ctr, Istanbul, Turkiye; [Turker, Fatih] Haseki Training & Res Hosp, Dept Internal Med, Turkiye, Istanbul, Turkiye; [Tokat, Yaman] Int Liver Ctr ILC, Istanbul, Turkiye; [Anilir, Ender] Istanbul Aydin Univ, Med Pk Florya Hastanesi, Organ Nakli Merkezi, Istanbul, Turkiye | en_US |
dc.authorid | Anılır, Ender/0000-0002-0024-1790 | |
dc.identifier.pmid | 37822306 | en_US |
dc.identifier.scopus | 2-s2.0-85172390791 | en_US |
dc.identifier.wos | WOS:001078775900003 | en_US |
dc.authorwosid | Anılır, Ender/F-5362-2017 | |