Boric acid-impregnated silk fibroin/gelatin/hyaluronic acid-based films for improving the wound healing process
dc.contributor.author | Özen N. | |
dc.contributor.author | Özbaş Z. | |
dc.contributor.author | İzbudak B. | |
dc.contributor.author | Emik S. | |
dc.contributor.author | Özkahraman B. | |
dc.contributor.author | Bal-Öztürk A. | |
dc.date.accessioned | 2024-02-04T13:30:03Z | |
dc.date.available | 2024-02-04T13:30:03Z | |
dc.date.issued | 2022 | |
dc.identifier.issn | 00218995 | |
dc.identifier.uri | https://doi.org/10.1002/app.51715 | |
dc.identifier.uri | http://hdl.handle.net/11446/4832 | |
dc.description.abstract | Recently, with the progression in wound dressings, the importance of the biocompatible material with enhanced features for potential applications in the biomedical field has been more developed. Current strategies focus on the acceleration of the wound healing by systematically designed dressing materials. In this study, biocompatible hydrogel films with the combination of silk fibroin, hyaluronic acid and gelatin biopolymers were fabricated. To gain the enhanced wound healing behavior of wound dressings, boric acid (BA) was formulated in various ratios. The prepared hydrogel films were characterized in terms of FTIR, TGA, DSC, and SEM analysis. Following to the swelling and mechanical tests, in vitro biocompatibility and wound healing tests were performed against L929 fibroblast cell line. Results suggest that the presence of 1% (wt/vol) BA in the formulation of silk fibroin/gelatin/hyaluronic acid based hydrogel films is the key in providing such an enhanced mechanical and wound healing feature and may offer an alternative approach for wound healing treatment. © 2021 Wiley Periodicals LLC. | en_US |
dc.description.sponsorship | 2019/01 | en_US |
dc.description.sponsorship | Research Fund of Demiroglu Bilim University (Grant number 2019/01) supported this work. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | John Wiley and Sons Inc | en_US |
dc.relation.ispartof | Journal of Applied Polymer Science | en_US |
dc.identifier.doi | 10.1002/app.51715 | |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | biomaterials | en_US |
dc.subject | differential scanning calorimetry | en_US |
dc.subject | films | en_US |
dc.subject | mechanical properties | en_US |
dc.subject | thermogravimetric analysis | en_US |
dc.subject | Biocompatibility | en_US |
dc.subject | Biopolymers | en_US |
dc.subject | Boric acid | en_US |
dc.subject | Boride coatings | en_US |
dc.subject | Cell culture | en_US |
dc.subject | Crosslinking | en_US |
dc.subject | Hyaluronic acid | en_US |
dc.subject | Hydrogels | en_US |
dc.subject | Swelling | en_US |
dc.subject | Thermogravimetric analysis | en_US |
dc.subject | Tissue regeneration | en_US |
dc.subject | 'current | en_US |
dc.subject | Biomedical fields | en_US |
dc.subject | FTIR analysis | en_US |
dc.subject | FTIR-TGA | en_US |
dc.subject | Hydrogel films | en_US |
dc.subject | Mechanical | en_US |
dc.subject | Silk fibroin | en_US |
dc.subject | Wound dressings | en_US |
dc.subject | Wound healing | en_US |
dc.subject | Wound healing process | en_US |
dc.subject | Differential scanning calorimetry | en_US |
dc.title | Boric acid-impregnated silk fibroin/gelatin/hyaluronic acid-based films for improving the wound healing process | en_US |
dc.type | article | en_US |
dc.department | DBÜ | en_US |
dc.identifier.issue | 9 | en_US |
dc.identifier.volume | 139 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.department-temp | Özen, N., Florence Nightingale Hospital School of Nursing, Demiroğlu Bilim University, Istanbul, Turkey; Özbaş, Z., Faculty of Engineering, Chemical Engineering Department, Çankırı Karatekin University, Cankiri, Turkey; İzbudak, B., Department of Stem Cell and Tissue Engineering, Institute of Health Sciences, Istinye University, Istanbul, Turkey; Emik, S., Faculty of Engineering, Chemical Engineering Department, Istanbul University-Cerrahpaşa, Istanbul, Turkey; Özkahraman, B., Faculty of Engineering, Polymer Materials Engineering Department, Hitit University, Corum, Turkey; Bal-Öztürk, A., Department of Stem Cell and Tissue Engineering, Institute of Health Sciences, Istinye University, Istanbul, Turkey, Faculty of Pharmacy, Department of Analytical Chemistry, Istinye University, Istanbul, Turkey, 3D Bioprinting Design & Prototyping R&D Center, Istinye University, Istanbul, Turkey | en_US |
dc.identifier.scopus | 2-s2.0-85116110558 | en_US |
dc.authorscopusid | 57142242000 | |
dc.authorscopusid | 8547715300 | |
dc.authorscopusid | 57221779519 | |
dc.authorscopusid | 12778407100 | |
dc.authorscopusid | 37112868500 | |
dc.authorscopusid | 57062000100 |
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