Spontan ve invitro fetilizasyon (IVF) ikiz gebeliklerin obstetrik ve perinatal sonuçlarinin karsilastirilmasi

Abstract

Amaç: Spontan ikiz gebelikler ile invitro fertilizasyon (IVF) yöntemi ile gerçeklesen ikiz gebeliklerin perinatal ve obstetrik sonuçlarini karsilastirmayi ve analiz etmeyi amaçladik. Gereç ve Yöntem: Ocak 2016-Ocak 2021 tarihleri arasinda üçüncü basamak perinatoloji merkezinde IVF yöntemiyle veya spontan sekilde gerçeklesen ikiz gebeler retrospektif olarak çalismaya dahil edildi. Gebelerin demografik verileri (cinsiyet, yas, gebelik haftasi) ve dogum sekilleri (spontan ve IVF) analiz edildi. Gebelerde görülen erken membran yirtilmasi (EMR), preterm dogum (PD) ve intrauterin büyüme geriligi (IUBG) sikliklari kaydedildi. Ayrica apgar skorlari, fetal anomalilerin varligi, yenidogan yogun bakim (YYB) ihtiyaci ve mortalite oranlari analiz edildi. Bulgular: Toplam 261 ikiz gebe çalismaya dahil edildi. Ortanca yas 29 (en az 15-en fazla 40 yil) ve %23,8 ‘i =35 yasindaydi. Spontan ve IVF gebelik oranlari, sirasiyla, %75,9 ve %24,1 idi. Ikiz gebeliklerde en sik görülen sorunlar sirasiyla EMR (%14,6), PD (%13,4), GHT (%11,5), oligohidramnios (%6,1), GDM (%4,6) ve polihidramnios (%2,3) idi. Ayrica %13,8’inde IUBG vardi. IVF gebelerin ortanca yasi, spontan gebelere göre anlamli derecede daha yüksekti (33,0-28,0) (p

Aim: We aimed to compare and analyze the perinatal and obstetric outcomes of in vitro fertilization (IVF) method and spontaneous twin pregnancies. Material and Method: Pregnant women who had had IVF and those with spontaneous fertilization in a tertiary perinatology center between January 2016 and January 2021 were retrospectively included in this study. The demographic data of the women (gender, age, gestational week) and fertilization types (spontaneous or IVF) were analyzed. Premature rupture of membranes (PROM), preterm delivery (PD), and intrauterine growth restriction (IUGR) was recorded. Additionally, Apgar scores, the presence of fetal anomalies, the need for neonatal intensive care (NICU) and mortality were analyzed. Results: Overall, 261 women who were pregnant with twins were included in this study. The median age of the mothers was 29 years (min 15-max 40 years), and 23.8% were =35 years. Spontaneous and IVF pregnancies occurred in 75.9% and 24.1%, respectively. The most common problems in the twin pregnancies were PROM (14.6%), PD (13.4%), GHT (11.5%), oligohydramnios (6.1%), GDM (4.6%), and polyhydramnios (2.3%). Also, 13.8% had IUGR. The median age of the women with IVF pregnancies was higher than the spontaneous pregnancies (33.0 vs 28.0 years) (p