Effects of curcumin supplementation on liver metabolism in rats fed a high-fat diet: A proteomic approach

Abstract

Background: In the modern world, many individuals routinely consume diets rich in animal fat, leading to a high incidence ofobesity. Curcumin (diferuloylmethane, turmeric) extracted from the dried root of the rhizome Curcuma longa, is a popular Asian dietary spice used in curry. Curcumin is the most active component of turmeric, comprising 2-8% by weight. Proteomics is an important tool for elucidating the cellular response to various treatments including dietary factors.