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Melatonin prevents mitochondrial damage induced by doxorubicin in mouse fibroblasts through Ampk-Ppar gamma-dependent mechanisms.
(Medical Science International, 2016)
Background: Doxorubicin (brand name: Adriamycin®) is used to treat solid tissue cancer but it also affects noncancerous tissues. Its mechanism of cytotoxicity is probably related to increased oxidation, mitochondrial ...