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dc.contributor.authorÖzdemir, Emrah
dc.contributor.authorYıldırımtürk, Özlem
dc.contributor.authorCengiz, Betül
dc.contributor.authorYurdakul, Selen
dc.contributor.authorAytekin, Saide
dc.date.accessioned2014-12-01T12:33:20Z
dc.date.available2014-12-01T12:33:20Z
dc.date.issued2014
dc.identifier.citationOzdemir E, Yildirimturk O, Cengiz B, Yurdakul S, Aytekin S. Evaluation of carotid intima-media thickness and aortic elasticity in patients with nondipper hypertension. Echocardiography. 2014; 31(5): 663-8. doi: 10.1111/echo.12444.en_US
dc.identifier.issn0742-2822
dc.identifier.urihttp://onlinelibrary.wiley.com/doi/10.1111/echo.12444/pdfen_US
dc.identifier.urihttps://hdl.handle.net/11446/588en_US
dc.descriptionİstanbul Bilim Üniversitesi, Tıp Fakültesi.en_US
dc.description.abstractBackgroundThe relationship between cardiovascular diseases and the diurnal blood pressure (BP) rhythm was researched in many studies. It has been demonstrated that the nondipping pattern has been associated with target organ damage and worsened cardiovascular outcomes. The aim of our study was to assess the relationship between aortic elasticity parameters and carotid intima-media thickness (CIMT) and diastolic dysfunction in terms of dipper and nondipper hypertension subtypes. MethodsA total of 60 hypertensive patients without known coronary heart disease were recruited to our study. All patients were classified as dipper or nondipper after ambulatory BP follow-up. Patients' left ventricular (LV) systolic and diastolic functions were assessed with transthoracic echocardiography. Ascending aorta diameters and CIMT were measured by ultrasonography and the elasticity parameters of aorta were calculated by using relevant formula. ResultsThere were no significant differences between the groups with respect to demographic, biochemical data, and cardiovascular risk factors. Aortic stiffness was significantly increased in nondippers, whereas aortic strain and distensibility were significantly decreased (P=0.005, P=0.005, and P=0.024, respectively). Carotid artery IMT was significantly increased in nondippers compared to dippers (P=0.013). A significant correlation was noted between CIMT and mean BP. No significant difference was detected between 2 groups in terms of LV hypertrophy and diastolic dysfunction. ConclusionIn our study, we showed that impairment of aortic elasticity parameters and increase in CIMT as a predictor of end organ damage were more often in the nondipper hypertensive patients.en_US
dc.language.isoengen_US
dc.publisherWiley-Blackwellen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectnondipper hypertensionen_US
dc.subjectcarotid intima-media thicknessen_US
dc.subjectaortic stiffnessen_US
dc.titleEvaluation of carotid intima- media thickness and aortic elasticity in patients with nondipper hypertensionen_US
dc.typearticleen_US
dc.relation.journalEchocardiographyen_US
dc.departmentDBÜ, Tıp Fakültesien_US
dc.identifier.issue5
dc.identifier.volume31
dc.identifier.startpage663
dc.identifier.endpage668
dc.contributor.authorIDTR141059en_US
dc.contributor.authorIDTR123116en_US
dc.contributor.authorIDTR140950en_US
dc.relation.publicationcategoryBelirsizen_US


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