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dc.contributor.authorÖzkara, Ahmet
dc.contributor.authorHatemi, Alican
dc.contributor.authorMert, Murat
dc.contributor.authorKöner, Özge
dc.contributor.authorÇetin, Gürkan
dc.contributor.authorGürsoy, Mete
dc.contributor.authorSüzer, Süzer
dc.identifier.citationOzkara A, Hatemi A, Mert M, Koner O, Cetin G, Gursoy M, Celebi S, Erdem CC, Haydin S, Yildiz CE, Suzer K. The effects of internal thoracic artery preparation with intact pleura on respiratory function and patients' early outcomes. Anadolu Kardiyoloji Dergisi. 2008; 8(5): 368-373.en_US
dc.descriptionİstanbul Bilim Üniversitesi, Tıp Fakültesi.en_US
dc.description.abstractOBJECTIVE: Postoperative respiratory functions, arterial blood gases, blood loss and clinical outcome following coronary artery bypass surgery (CABG) were assessed in a prospective randomized single-blind (patient- blind) clinical study comparing two different techniques of internal thoracic artery (ITA) harvesting. METHODS: Fifty-four patients admitted for CABG were allocated into two groups according to 'random numbers' technique. In a Group 1 (n=26) ITA was prepared keeping the pleura intact and in a Group 2 (n=28) pleura was opened. Both groups were compared in terms of postoperative respiratoryfunctions, arterial blood gases, bleeding and clinical outcomes using ANOVA for repeated measurements analysis. RESULTS: Analysis of spirometric and partial oxygen pressure data showed that postoperative reductions in forced expiratory volume (0.17+/-0.18 lt vs. 0.28+/-0.14 lt, p=0.016), forced vital capacity (0.18+/-0.19 lt vs. 0.28+/-0.13 lt, p=0.037) and arterial oxygen measurements (-0.03+/-0.22 mmHg vs. 0.15+/-0.4 mmHg, p=0.023) were less pronounced in patients of Group 1 as compared with patients of Group 2. The increase in intrapulmonary shunts (Qs/Qt ratio) after the operation was more pronounced in Group 2 patients than in Group 1 patients (p<0.01) and the mean values of Qs/Qt ratio 24 hours after the operation were higher in group 2 as compared to Group 1 patients(0.100+/-0.063 vs. 0.054+/-0.048, p=0.001). Radiological evaluation revealed that costophrenic angle obliteration after operation more often occurred in Group 2 (14/28 patients) than in Group 1 (0/26 patients) (p<0.0001). Cardiothoracic index increased significantly after operation only in group 2 patients (p=0.001). Postoperative blood loss within 24 hours was significantly lower in Group 1 compared to Group 2 (656+/-179 ml vs. 907+/-257 ml, p=0.001). There was no significant difference between groups in the ICU stay duration (p=0.186), whereas the hospital stay was significantly longer in group 2 patients than in Group 1 patients (8.8+/-2.0 days vs. 7.6+/-2.0 days, p=0.039). CONCLUSION: According to our results, preserving pleural integrity has positive effects on the respiratory functions and patients' clinical outcomesfollowing CABG operations.en_US
dc.publisherAves Yayinciliken_US
dc.subjectcoronary artery bypass surgeryen_US
dc.subjectinternal thoracic artery harvestingen_US
dc.subjectintact pleuraen_US
dc.titleThe effects of internal thoracic artery preparation with intact pleura on respiratory function and patients' early outcomesen_US
dc.title.alternativePlörotomi yap›lmaks›z›n internal torasik arter grefti haz›rlanmas›n›n solunum fonksiyonlar› ve erken dönem iyileflme periyodu üzerine etkilerien_US
dc.relation.journalAnadolu Kardiyoloji Dergisien_US
dc.contributor.departmentDBÜ, Tıp Fakültesien_US

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