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dc.contributor.authorGüdücü, Nilgün
dc.contributor.authorİşçi, Herman
dc.contributor.authorBaşgül Yiğiter, Alin
dc.contributor.authorDünder, İlkkan
dc.date.accessioned2014-12-31T09:41:08Z
dc.date.available2014-12-31T09:41:08Z
dc.date.issued2012
dc.identifier.citationGuducu N, Isci H, Basgul-Yigiter A, Dunder I. C-reactive protein and lipoprotein-a as markers of coronary heart disease in polycystic ovary syndrome. Journal of the Turkish-German Gynecological Association. 2012; 13(4): 227-232. doi: 10.5152/jtgga.2012.35.en_US
dc.identifier.issn1309-0399
dc.identifier.urihttp://www.jtgga.org/sayilar/50/buyuk/JTGGA_13_4_227_232.pdfen_US
dc.identifier.urihttps://hdl.handle.net/11446/641en_US
dc.descriptionİstanbul Bilim Üniversitesi, Tıp Fakültesi.en_US
dc.description.abstractOBJECTIVE: The aim of this study was to investigate the risk factors of coronary heart disease, CRP and Lipoprotein-a in polycystic ovary syndrome patients. MATERIAL AND METHODS: Prospectively collected data of polycystic ovary syndrome patients (n=62) and control group (n=40) were compared. RESULTS: PCOS patients had higher HOMA-IR, CRP, DHEAS, free testosterone, FAI, LH and prolactin levels when compared to the control group. Lipoprotein-a levels did not differ between the groups. The obese PCOS group had statistically significantly higher fasting blood glucose, total cholesterol, triglyceride, free testosterone, insulin, CRP and HOMA-IR and statistically significantly lower HDL and SHBG when compared to normal weight PCOS persons. Fasting blood glucose, total cholesterol, LDL, SHBG, CRP, Lipoprotein-a, FSH, LH, TSH, DHEAS and prolactin levels did not differ between the normal weight and obese control groups. CONCLUSION: CRP levels increase in polycystic ovary syndrome patients and can be used as a marker of coronary heart disease. Future studies can be directed at treatments to decrease CRP levels, including antiinflammatory treatments.en_US
dc.description.abstractAmaç: Bu çalışmanın amacı polikistik over sendromlu hastalarda koroner kalp hastalıkları risk faktörlerini, CRP ve Lipoprotein-a araştırmaktı. Gereç ve Yöntemler: Prospektif olarak polikistik over sendromlu (n=62) ve kontrol grubunun (n=40) kan örnekleri çalışıldı. Bulgular: Polikistik over sendromlu hastalarda HOMA-IR, CRP, DHEAS, serbest testosteron, FAI, LH and prolaktin seviyeleri yüksek, FSH ve SHBG seviyeleri ise düşük bulundu. Lipoprotein-a gruplarda farklı değildi. Obez polikistik over sendromlu hastalarda açlık kan şekeri, total kolesterol, trigliserit, serbest testosteron, insulin, CRP ve HOMAIR daha yüksek, HDL ve SHBG daha düşük bulundu. Açlık kan şekeri, total kolesterol, LDL, CRP, SHBG, Lipoprotein-a, FSH, LH, TSH, DHEAS ve prolaktin seviyeleri obez ve normal kilolu kontrol gruplarında benzerdien_US
dc.language.isoengen_US
dc.publisherAves Yayıncılıken_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectpolycystic ovary syndromeen_US
dc.subjectobesityen_US
dc.subjectCRPen_US
dc.subjectlipoprotein-aen_US
dc.subjectcoronary heart diseaseen_US
dc.subjectpolikistik over sendromuen_US
dc.subjectobesiteen_US
dc.subjectkoroner kalp hastalığıen_US
dc.titleC-reactive protein and lipoprotein-a as markers of coronary heart disease in polycystic ovary syndromeen_US
dc.title.alternativePolikistik over sendromlu hastalarda koroner kalp hastalıklarının belirteci olarak c-reaktif protein ve lipoprotein-a bakılmasıen_US
dc.typearticleen_US
dc.relation.journalJournal of the Turkish-German Gynecological Associationen_US
dc.departmentDBÜ, Tıp Fakültesien_US
dc.identifier.issue4
dc.identifier.volume13
dc.identifier.startpage227
dc.identifier.endpage232
dc.contributor.authorIDTR123126en_US
dc.contributor.authorIDTR123093en_US
dc.contributor.authorIDTR122849en_US
dc.contributor.authorIDTR26039en_US
dc.relation.publicationcategoryBelirsizen_US


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