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Effect of epidermal growth factor receptor status on the outcomes of patients with metastatic gastric cancer: A pilot study

dc.contributor.authorAydın, Kübra
dc.contributor.authorOkutur, S. Kerem
dc.contributor.authorBozkurt, Mustafa
dc.contributor.authorTürkmen, İlknur
dc.contributor.authorNamal, Esat
dc.contributor.authorPilancı, Kezban Nur
dc.contributor.authorDemir, Osman Gökhan
dc.date.accessioned2015-01-09T09:07:58Z
dc.date.available2015-01-09T09:07:58Z
dc.date.issued2014
dc.date.issued1
dc.identifier.citationAydin K, Okutur SK, Bozkurt M, Turkmen I, Namal E, Pilanci K, Ozturk A, Akcali Z, Dogusoy G, Demir OG . Effect of epidermal growth factor receptor status on the outcomes of patients with metastatic gastric cancer: A pilot study. Oncology Letters. 2014; 7(1): 255-259.en_US
dc.identifier.issn1792-1074
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861593/pdf/ol-07-01-0255.pdfen_US
dc.identifier.urihttps://hdl.handle.net/11446/650en_US
dc.descriptionİstanbul Bilim Üniversitesi, Tıp Fakültesi.en_US
dc.description.abstractThe expression of epidermal growth factor receptor (EGFR) has been linked to clinical outcome in several solid tumors. However, the clinical significance of EGFR (c-erbB1) in gastric cancer remains unclear. The present study was designed to detect the clinical implications of EGFR in the Turkish population. Paraffin-embedded tissue microarrays containing gastric cancer tissue were obtained from 30 patients. EGFR expression was detected using immunohistochemistry. The correlation of this biomarker to the clinicopathological features and survival of patients with gastriccancer was studied. The overall positivity rate of EGFR was 63.3%. EGFR expression was significantly correlated with an improved progression-free survival (PFS) and overall survival (OS) rate (P=0.039 and 0.01, respectively). EGFR expression is a good prognostic marker for patients withgastric cancer.en_US
dc.language.isoengen_US
dc.publisherSpandidos Publicationsen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectepidermal growth factor receptoren_US
dc.subjectgastric canceren_US
dc.subjectprognosisen_US
dc.titleEffect of epidermal growth factor receptor status on the outcomes of patients with metastatic gastric cancer: A pilot studyen_US
dc.typearticleen_US
dc.relation.journalOncology Lettersen_US
dc.departmentDBÜ, Tıp Fakültesien_US
dc.identifier.volume7
dc.identifier.startpage255
dc.identifier.endpage259
dc.contributor.authorIDTR141527en_US
dc.contributor.authorIDTR141515en_US
dc.contributor.authorIDTR199897en_US
dc.contributor.authorIDTR183371en_US
dc.contributor.authorIDTR143794en_US
dc.contributor.authorIDTR168000en_US
dc.contributor.authorIDTR149167en_US
dc.contributor.authorIDTR4330en_US
dc.contributor.authorIDTR100576en_US
dc.contributor.authorIDTR141516en_US
dc.relation.publicationcategoryBelirsizen_US


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