Analysis of the complement pathway mutations in atypical hemolytic uremic syndrome (AHUS)
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CitationHancer VS, Guvenc S, Hindilerden F, Buyukdogan M, Diz-Kucukkaya R. (2014). Analysis of the complement pathway mutations in atypical hemolytic uremic syndrome (AHUS). Thrombosis Research. 2014: S35–S123. 23rd MLTD Biennial International Congress on Thrombosis. Valencia, May 14-17, 2014
Background: HUS is characterized by hemolytic anemia, thrombocytopenia, and renal failure caused by platelet thrombi in the microcirculation of the kidney and other organs. Typical HUS is triggered by infectious agents such as strains of E. coli that produce powerful Shiga-like exotoxins, whereas AHUS can be genetic, acquired, or idiopathic.