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dc.contributor.authorGönenç, Gökçenur
dc.contributor.authorİşçi, Herman
dc.contributor.authorBaşgül Yiğiter, Alin
dc.contributor.authorHançer, Veysel
dc.contributor.authorBüyükdoğan, Murat
dc.contributor.authorGüdücü, Nilgün
dc.contributor.authorDünder, İlkkan
dc.date.accessioned2015-09-10T07:44:03Z
dc.date.available2015-09-10T07:44:03Z
dc.date.issued2015
dc.identifier.citationGonenc G, Isci H, Yigiter AB, Hancer V, Buyukdogan M, Guducu N, Dunder I. Non-invasive prenatal diagnosis of fetal RhD by using free fetal DNA. Clin Exp Obstet Gynecol. 2015;42(3):344-6.en_US
dc.identifier.issn0390-6663
dc.identifier.urihttp://www.irog.net/en-CA/en_US
dc.identifier.urihttps://hdl.handle.net/11446/770en_US
dc.descriptionİstanbul Bilim Üniversitesi, Tıp Fakültesi.en_US
dc.description.abstractObjective: Anti-D immunoglobulin is applied to all pregnant women having RhD incompatibility to prevent hemolytic disease of the newborn. The aim of this study is to determine fetal RhD status in the Rh incompatible pregnancies with an non-invasive technique; free fetal DNA isolation from maternal circulation. In the case of Rh incompatibility especially with a history of previous fetal anemia, it can be beneficial to know Rh status antenatally in terms of monitoring fetuses with Rh positive [RhD(+)] status consciously. Materials and Methods: Total free DNA was isolated in 50 Rh negative [RhD(-)] pregnant women, who had RhD alloimmunisation with their husbands. The gene in isolated DNA was investigated with TagMan prob and real time PCR by using primers belonging to exon 7 of the RhD gene.en_US
dc.language.isoengen_US
dc.publisherUniversità di Padova.en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectprenatal diagnosisen_US
dc.subjectfetal DNAen_US
dc.subjectRhD geneen_US
dc.titleNon-invasive prenatal diagnosis of fetal RhD by using free fetal DNA.en_US
dc.typearticleen_US
dc.relation.journalClinical and experimental obstetrics & gynecologyen_US
dc.contributor.departmentDBÜ, Tıp Fakültesien_US
dc.identifier.issue3
dc.identifier.volume42
dc.identifier.startpage344
dc.identifier.endpage346
dc.contributor.authorIDTR141251en_US
dc.contributor.authorIDTR123093en_US
dc.contributor.authorIDTR122849en_US
dc.contributor.authorIDTR43513en_US
dc.contributor.authorIDTR123126en_US
dc.contributor.authorIDTR26039en_US
dc.relation.publicationcategoryBelirsizen_US


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