The role of ultrasonographic findings to predict molecular subtype, histologic grade, and hormone receptor status of breast cancer
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info:eu-repo/semantics/openAccessDate
2015Author
Çelebi, FilizPilancı, Kezban Nur
Ordu, Çetin
Ağaçayak, Filiz
Alço, Gül
İlgün, Serkan
Özmen, Vahit
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Celebi F, Pilanci KN, Ordu C, Agacayak F, Alco G, Ilgun S, Sarsenov D, Erdogan Z, Ozmen V. The role of ultrasonographic findings to predict molecular subtype, histologic grade, and hormone receptor status of breast cancer. Diagn Interv Radiol 2015; 21(6): 448-453. doi:10.5152/dir.2015.14515Abstract
Purpose: The correlation between imaging findings and pathologic characteristics of tumors may provide information for diagnosis and treatment of cancer. The aim of this study is to determine whether ultrasound features of breast cancer are associated with molecular subtype, histologic grade, and hormone receptor status, as well as assess the predictive value of these features.
Methods: A total of 201 consecutive invasive breast cancer patients were reviewed from the database according to the Breast Imaging and Reporting Data System (BI-RADS). Tumor margins were classified as circumscribed and noncircumscribed. Noncircumscribed group was divided into indistinct, spiculated, angular, and microlobulated. The posterior acoustic features were divided into four categories: shadowing, enhancement, no change, and mixed pattern.