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Beneficial effects of agomelatine in experimental model of sepsis-related acute kidney injury.

dc.contributor.authorBaşol, Nurşah
dc.contributor.authorErbaş, Oytun
dc.contributor.authorÇavuşoğlu, Türker
dc.contributor.authorMeral, Ayfer
dc.contributor.authorAteş, Utku
dc.date.accessioned2016-06-10T09:32:34Z
dc.date.available2016-06-10T09:32:34Z
dc.date.issued2016
dc.identifier.citationBasol N, Erbas O, Cavusoglu T, Meral A, Ates U. Beneficial effects of agomelatine in experimental model of sepsis-related acute kidney injury. Ulus Travma Acil Cerrahi Derg. 2016; 22(2):121-126. doi: 10.5505/tjtes.2015.29499.en_US
dc.identifier.issn1306-696X
dc.identifier.urihttp://www.tjtes.org/eng/jvi.aspxen_US
dc.identifier.urihttps://hdl.handle.net/11446/969en_US
dc.descriptionİstanbul Bilim Üniversitesi, Tıp Fakültesi.en_US
dc.description.abstractBackground: Sepsis-related acute kidney injury (AKI) is a serious complication of sepsis. Problems persist regarding early diagnosis and treatment of AKI. The aim of the present study was to evaluate the efficacy of agomelatine, which is primarily known for its positive effects on depressive and anxiety disorders in sepsis-related AKI. Methods: Sepsis model was created with cecal ligation puncture (CLP). Rats were separated into 4 groups of 8 each: the control group, the sham-operated group, the CLP+saline group, and the CLP+agomelatine group. Agomelatine was administered intraperitoneally in doses of 20 mg/kg.en_US
dc.language.isoengen_US
dc.publisherUlusal Travma ve Acil Cerrahi Derneğien_US
dc.identifier.doi10.5505/tjtes.2015.29499.en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectacute kidney injuryen_US
dc.subjectagomelatineen_US
dc.subjectcecal ligation punctureen_US
dc.subjectsepsisen_US
dc.titleBeneficial effects of agomelatine in experimental model of sepsis-related acute kidney injury.en_US
dc.typearticleen_US
dc.relation.journalUlusal Travma Ve Acil Cerrahi Dergisien_US
dc.departmentDBÜ, Tıp Fakültesien_US
dc.identifier.issue2
dc.identifier.volume22
dc.identifier.startpage121
dc.identifier.endpage126
dc.contributor.authorIDTR18420en_US
dc.contributor.authorIDTR44788en_US
dc.contributor.authorIDTR162706en_US
dc.contributor.authorIDTR106139en_US
dc.relation.publicationcategoryBelirsizen_US


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